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Major Depressive Disorder clinical trials in San Diego, CA
16 studies for Major Depressive Disorder are looking for participants at sites in and around San Diego (within about 30 miles). Open a study to see who can join and how to contact the study team.
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ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
RecruitingPhase 2
- Kadima Neuropsychiatry Institute, La Jolla · 11 mi away
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
RecruitingPhase 3
- Kadima Neuropsychiatry Institute, San Diego
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 2
- Artemis Institute For Clinical Research - San Diego, San Diego
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
RecruitingPhase 4
- Neurocrine Clinical Site, San Diego
Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study
Recruiting
- UCSD Interventional Psychiatry, San Diego
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
RecruitingPhase 3
- Artemis Institute for Clinical Research, San Diego
- Center for Neurohealth, La Jolla · 11 mi away
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
RecruitingPhase 2
- Draig Clinical Site, San Diego
Enhancing Veteran-Clinical Collaboration in VA PRRCs
Recruiting
- VA San Diego Healthcare System, San Diego, CA, San Diego
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
RecruitingPhase 3
- Clinical Research Site, San Diego
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, San Diego
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
RecruitingPhase 2
- Kadima Neuropsychiatry Institute, La Jolla · 11 mi away
Mindfulness Engaged Neurostimulation for Depression (MEND II)
RecruitingPhase 2
- UC San Diego Health Psychiatry, San Diego
Maintenance rTMS for Depression (Maitr-De)
Recruiting
- University of California, San Diego, San Diego
ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
RecruitingObservational study
- Salma Health, La Jolla · 11 mi away
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, San Diego
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
RecruitingPhase 4
- Clinical Research Site, San Diego
Major Depressive Disorder trials in other cities
- New York City, NY36 studies
- Boston, MA31 studies
- Atlanta, GA25 studies
- Philadelphia, PA23 studies
- Orlando, FL19 studies
- Miami, FL18 studies
- Chicago, IL17 studies
- Tampa, FL17 studies
- Houston, TX16 studies
- Little Rock, AR14 studies
- Austin, TX13 studies
- Las Vegas, NV13 studies
Other studies in San Diego
- Non-Small Cell Lung Cancer48 studies
- Breast Cancer41 studies
- Cancer (all types)32 studies
- Prostate Cancer31 studies
- Metastatic Cancer30 studies
- Colorectal Cancer25 studies
- Ovarian Cancer24 studies
- Pancreatic Cancer24 studies
- Lung Cancer23 studies
- Obesity23 studies
- Heart Failure23 studies
- Depression21 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.