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Heart Failure clinical trials in Seattle, WA

17 studies for Heart Failure are looking for participants at sites in and around Seattle (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

RecruitingPhase 3
  • Virginia Mason Medical Center, Seattle
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288

A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)

RecruitingPhase 2
  • Local Institution - 132, Seattle
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

RecruitingPhase 2/3
  • Seattle Children's Hospital-Cardiology/Fetal Therapy ( Site 0019), Seattle
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

RecruitingPhase 2
  • Swedish Heart & Vascular Institute, Advanced Cardiac Support Program, Seattle
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

RecruitingPhase 3
  • Tenax Investigational Site, Seattle
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Swedish Medical Center_Seattle, Seattle
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

RecruitingPhase 2
  • Seattle Children's Hospital, Seattle
Ages 0 to 16 · All sexes · Updated Aug 10, 2026 · NCT06080074

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • Swedish Medical Center, Seattle
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

Repurposing Valsartan May Protect Against Pulmonary Hypertension

RecruitingPhase 2
  • University of Washington Medical Center, Seattle
Ages 18 to 80 · All sexes · Updated May 4, 2026 · NCT06053580

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

RecruitingPhase 3
  • University of Washington, Seattle
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

Recruiting
  • University of Washington Medical Center, Seattle
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06895070

Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV

Recruiting
  • University of Washington, Seattle
Ages 40 and older · All sexes · Updated Mar 16, 2026 · NCT07105007

Left vs Left Randomized Clinical Trial

Recruiting
  • University of Washington, Seattle
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658

Cardiogenic Shock Working Group Registry

RecruitingObservational study
  • University of Washington Medical Center, Seattle
Ages 18 and older · All sexes · Updated Jun 6, 2025 · NCT04682483

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

RecruitingPhase 1/2
  • University of Washington Medicine, Seattle
Ages 18 to 80 · All sexes · Updated Mar 26, 2024 · NCT04703842

Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD Patients

Recruiting
  • University of Washington Medical Center, Seattle
Ages 18 and older · All sexes · Updated Feb 23, 2021 · NCT02537769

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Seattle

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.