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Depression clinical trials in Oklahoma City, OK

5 studies for Depression are looking for participants at sites in and around Oklahoma City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

RecruitingPhase 3
  • Sooner Clinical Research, Oklahoma City
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • University of Oklahoma Health Sciences Center, Oklahoma City
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • Pahl Pharmaceutical Professionals Llc, Oklahoma City
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Oklahoma City
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Oklahoma City

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.