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Heart Failure clinical trials in Indianapolis, IN
23 studies for Heart Failure are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
RecruitingPhase 3
- St. Francis Medical Group-Indiana Heart Physicians, Inc, Indianapolis
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
RecruitingPhase 3
- St. Francis Medical Group-Indiana Heart Physicians, Inc, Indianapolis
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
RecruitingPhase 3
- Research Site, Indianapolis
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
RecruitingPhase 3
- Ascension Medical Group, Indianapolis
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
RecruitingPhase 3
- Research Site, Indianapolis
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
RecruitingPhase 3
- Indianapolis, IN Investigative Site 10074, Indianapolis
- Indianapolis, IN Investigative Site 10008, Indianapolis
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Recruiting
- Ascension St. Vincent Hospital - Indianapolis, Indianapolis
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Recruiting
- Community Heart and Vascular Hospital, Indianapolis
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
RecruitingPhase 2
- Local Institution - 166, Indianapolis
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- Indianapolis, Indianapolis
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- Indiana. University, Indianapolis
- Franciscan Physician Network-Indiana Heart Physicians, Indianapolis
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
RecruitingPhase 3
- Tenax Investigational Site, Indianapolis
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- Indiana University Health Methodist Hospital, Indianapolis
Alleviant ALLAY-HF Study
Recruiting
- Indiana University, Indianapolis
Assessment of CCM in HF With Higher Ejection Fraction
Recruiting
- Ascension Medical Group St. Vincent, Indianapolis
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Riley Hospital For Children - Cardiology, Indianapolis
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
- Ascension St. Vincent's, Indianapolis
Pediatric Cardiomyopathy Mutation Analysis
RecruitingObservational study
- IU School of Medicine, Indianapolis
Palliative Care for People With HF
RecruitingObservational study
- IUHealth, Indianapolis
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Riley Hospital For Children - Cardiology, Indianapolis
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
- St. Vincent Hospital, Indianapolis
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- Community Health Network, Indianapolis
Left vs Left Randomized Clinical Trial
Recruiting
- Trustees of Indiana University, Indianapolis
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- New York City, NY51 studies
- Boston, MA44 studies
- Dallas, TX42 studies
- Houston, TX36 studies
- Cleveland, OH33 studies
- Chicago, IL31 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- St. Louis, MO26 studies
- Durham, NC26 studies
- Kansas City, MO25 studies
- Atlanta, GA25 studies
Other studies in Indianapolis
- Non-Small Cell Lung Cancer32 studies
- Cancer (all types)24 studies
- Breast Cancer20 studies
- Obesity20 studies
- Metastatic Cancer19 studies
- Colorectal Cancer18 studies
- Ovarian Cancer17 studies
- Lung Cancer16 studies
- Cardiovascular Disease16 studies
- Type 1 Diabetes14 studies
- Endometrial Cancer14 studies
- Alzheimer's Disease14 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.