Healthy volunteer studies in Cleveland, OH
94 studies at sites in and around Cleveland accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.
Investigating the Effect of the Non-nutritive Sweetener Sucralose in Inflammatory Bowel Disease
RecruitingHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
- UH Minoff Health Center, Chagrin Falls · 17 mi away
Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate
RecruitingHealthy volunteers welcome
- Cleveland Clinic Main, Cleveland
Comparing Reduction With ESD- Versus APC-TORe
RecruitingHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
A Study of COVID-19 Vaccine(s) in Children and Adults
RecruitingPhase 3Healthy volunteers welcome
- Senders Pediatrics, South Euclid · 9 mi away
Non-nutritive Sweeteners in Inflammatory Bowel Disease
RecruitingHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
- UH Minoff Health Center, Chagrin Falls · 17 mi away
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
RecruitingPhase 3Healthy volunteers welcome
- University Hospitals, Cleveland
- Senders Pediatrics, South Euclid · 9 mi away
Comparison of ALD, NASH, and Healthy Control Patients
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
RecruitingPhase 1/2Healthy volunteers welcome
- Velocity Clinical Research - Cleveland- Site Number : 8400024, Beachwood · 10 mi away
HA35 Acute Alcohol Study
RecruitingEarly phase 1Healthy volunteers welcome
- Cleveland Clinic, Cleveland
Peripheral Blood Mononuclear Cells Response In Healthy Controls, Heavy Drinkers, and Patients With Alcoholic Hepatitis
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)
RecruitingPhase 1Healthy volunteers welcome
- Velocity Clinical Research, Cleveland ( Site 0005), Cleveland
A Study of BLB-201 RSV Vaccine in Infants and Children
RecruitingPhase 1/2Healthy volunteers welcome
- Velocity Clinical Research, Cleveland, Beachwood · 10 mi away
Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)
RecruitingPhase 3Healthy volunteers welcome
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
RecruitingPhase 3Healthy volunteers welcome
- Case Western Reserve Department of Ophthalmology, Cleveland
PROSPECT Registry for Individuals at Risk for Genetic Prion Disease
RecruitingObservational studyHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
RecruitingHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
- Cleveland Clinic Taussig Cancer Center, Cleveland
Immediate Versus Delayed Loading of Maxillary Overdenture Implants
RecruitingHealthy volunteers welcome
- Case Western Reserve University Department of Periodontics, Cleveland
Development of MRF for Characterization of Brain Tumors After Radiotherapy
RecruitingHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland
- Cleveland Clinic Taussig Cancer Center, Cleveland
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
RecruitingPhase 3Healthy volunteers welcome
- Senders Pediatrics, South Euclid · 9 mi away
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
RecruitingObservational studyHealthy volunteers welcome
- University Hospitals Case Medical Center, Cleveland
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
RecruitingPhase 3Healthy volunteers welcome
- VA Northeast Ohio Healthcare System Louis Stokes Cleveland VA Medical Center, Cleveland
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
RecruitingPhase 3Healthy volunteers welcome
- Senders Pediatrics, South Euclid · 9 mi away
Quality of End-of-Life Care for Children With Cancer
RecruitingObservational studyHealthy volunteers welcome
- Rainbow Babies and Childrens Hospital, Cleveland
The Vanguard Study: Testing a New Way to Screen for Cancer
RecruitingHealthy volunteers welcome
- Louis Stokes Cleveland VA Medical Center, Cleveland
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
RecruitingPhase 4Healthy volunteers welcome
- Case Western Reserve University, Cleveland
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
RecruitingPhase 3Healthy volunteers welcome
- Senders Pediatrics, South Euclid · 9 mi away
Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis
RecruitingHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
RecruitingPhase 4Healthy volunteers welcome
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
RecruitingPhase 1/2Healthy volunteers welcome
- Local Institution - 0028, Cleveland
Robotic Versus Open Ventral Hernia Repair
RecruitingHealthy volunteers welcome
- University Hospitals, Cleveland
- Cleveland Clinic, Cleveland
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
RecruitingObservational studyHealthy volunteers welcome
- University Hospitals of Cleveland, Cleveland
- Cleveland Clinic, Cleveland
Fibrosis Lessens After Metabolic Surgery
RecruitingPhase 4Healthy volunteers welcome
- Cleveland Clinic, Cleveland
Longitudinal Validation of CIRC Technologies
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
RecruitingObservational studyHealthy volunteers welcome
- Case Western Reserve Medical Center, Cleveland
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Comprehensive HHT Outcomes Registry of the United States (CHORUS)
RecruitingObservational studyHealthy volunteers welcome
- The Cleveland Clinic, Cleveland
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
RecruitingHealthy volunteers welcome
- The Cleveland Clinic, Cleveland
Health-Related Quality of Life and Metabolic Outcomes in PCOS
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement
RecruitingObservational studyHealthy volunteers welcome
- Case Western Reserve University Department of Periodontics, Cleveland
BoxX-NoAF Clinical Trial
RecruitingHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
Cardiovascular and Metabolic Sciences Biorepository
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Main Campus, Cleveland
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
RecruitingObservational studyHealthy volunteers welcome
- Rainbow Babies & Children's Hospital, Cleveland
Healthy Aging in People With Epilepsy Program
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Corneal Elastography and Patient Specific Modeling
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Foundation Cole Eye Institute, Cleveland
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
RecruitingPhase 3Healthy volunteers welcome
- GSK Investigational Site, Cleveland
Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums
RecruitingHealthy volunteers welcome
- Case Western Reserve University School of Dental Medicine, Cleveland
Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
CV Imaging of Metabolic Interventions
RecruitingObservational studyHealthy volunteers welcome
- Cardiovascular Innovation Research Center, Cleveland
Development of CIRC Technologies
RecruitingObservational studyHealthy volunteers welcome
- Cardiovascular Innovation Research Center, Cleveland
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
RecruitingPhase 1Healthy volunteers welcome
- Senders Pediatrics, South Euclid · 9 mi away
Acellular Dermal Matrix Investigation in Breast Reconstruction
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Baby Steps to Care
RecruitingHealthy volunteers welcome
- University University Cleveland Medical Center, Cleveland
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
RecruitingPhase 3Healthy volunteers welcome
- Cleveland Clinic, Cleveland
Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy
RecruitingHealthy volunteers welcome
- MetroHealth Medical Center, Cleveland
- University Hospitals Rainbow Ahuja Women and Children's Center, Cleveland
Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry
RecruitingObservational studyHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
RecruitingPhase 3Healthy volunteers welcome
- Case Western Reserve University, Cleveland
Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial
RecruitingPhase 3Healthy volunteers welcome
- Case Western Reserve University, Cleveland
Cleveland African American Prostate Cancer Project
RecruitingHealthy volunteers welcome
- Barbershops Local to Cleveland, Cleveland
Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Neonatal Platelet Transfusion Threshold Trial
RecruitingHealthy volunteers welcome
- Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
RecruitingHealthy volunteers welcome
- Cleveland Clinic Main Campus, Cleveland
Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
RecruitingHealthy volunteers welcome
- Case Western Reserve University, Case Comprehensive Cancer Center, Cleveland
Preventing Athlete Under-fueling Through Nutrition.
RecruitingHealthy volunteers welcome
- Case Western Reserve University, Cleveland
Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
RecruitingObservational studyHealthy volunteers welcome
- Cole Eye Institute, Cleveland
Genetics of Uveitis
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
RecruitingObservational studyHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Caris Biorepository Research Protocol
RecruitingObservational studyHealthy volunteers welcome
- Great Lakes Medical Research, Cleveland
Home-based Vision Therapy
RecruitingPhase 1Healthy volunteers welcome
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Mechanisms of Malnutrition in Cirrhosis With Portosystemic Shunting
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic Foundation, Cleveland
Ethanol Induces Skeletal Muscle Autophagy
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Suture Repair vs Mesh Repair for Incisional Hernia
RecruitingHealthy volunteers welcome
- Cleveland Clinic Main Campus, Cleveland
Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery
RecruitingPhase 2/3Healthy volunteers welcome
- Cleveland Clinic Main Campus, Cleveland
Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery
RecruitingHealthy volunteers welcome
- University Hospitals Cleveland Medial Center, Cleveland
CGM for the Early Detection and Management of Hyperglycemia in Pregnancy
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
RecruitingPhase 4Healthy volunteers welcome
- Cleveland Clinic, Cleveland
Home BP Monitoring
RecruitingHealthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion
RecruitingPhase 1Healthy volunteers welcome
- University Hospitals Cleveland Medical Center, Cleveland
Imaging Assessments of ARPKD Kidney Disease Progression
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
LT Comparative Effectiveness of 2 Caries Treatments
RecruitingHealthy volunteers welcome
- Case Western Reserve University, Cleveland
Oral Health Intervention in Adult Primary Care
RecruitingHealthy volunteers welcome
- Case Western Reserve University, Cleveland
Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder
RecruitingObservational studyHealthy volunteers welcome
- University Hospitals Cleveland Medical Center - Mood Disorders Program, Cleveland
Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants
RecruitingHealthy volunteers welcome
- Thrive Neuromedical, LLC, Chagrin Falls · 17 mi away
Early Diagnosis of Pancreatic Cancer Duodenal Fluid-Based Biomarker Exploratory Study
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study
RecruitingHealthy volunteers welcome
- Cleveland Clinic, Cleveland
Evaluate the Safety and Effectiveness of the AccuraSee™ IOPCL for Secondary Implantation in the Capsular Bag to Improve Near and/or Intermediate Vision Following Previous Cataract Surgery
RecruitingHealthy volunteers welcome
- Midwest Vision Partners, Cleveland
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.