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Obesity clinical trials in Indianapolis, IN

20 studies for Obesity are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Franciscan Physician Network - Indiana Heart Physicians, Indianapolis
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

RecruitingPhase 3
  • IU Health - Riley Physicians Endo-Diab, Indianapolis
Ages 8 to 18 · All sexes · Updated Sep 30, 2026 · NCT07253285

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

RecruitingPhase 3
  • Midwest Inst For Clin Res, Indianapolis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07720271

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Midwest Inst For Clin Res, Indianapolis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Indiana University Health University Hospital, Indianapolis
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • Riley Hospital for Children, Indianapolis
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Indiana University Health University Hospital, Indianapolis
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

RecruitingPhase 3
  • Midwest Inst For Clin Res, Indianapolis
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07339423

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • DM Clinical Research - Indianapolis, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, Indianapolis
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Indianapolis
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • Ascension Medical Group, Indianapolis
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

RecruitingPhase 2
  • Investigators Research Group, Brownsburg · 14 mi away
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

RecruitingPhase 4
  • Dawes Fretzin Clinical Research Group, LLC, Indianapolis
  • The Indiana Clinical Trials Center, PC, Plainfield · 14 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

RecruitingPhase 3
  • Midwest Inst For Clin Res, Indianapolis
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07745504

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

RecruitingPhase 2
  • Indiana University School of Medicine, Indianapolis
Ages 11 to 18 · All sexes · Updated Aug 21, 2026 · NCT05414409

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Indiana University Health Methodist Hospital, Indianapolis
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents

RecruitingHealthy volunteers welcome
  • Indiana University Hospital, Indianapolis
Ages 12 to 18 · All sexes · Updated Aug 6, 2026 · NCT07223151

Fibrosis Lessens After Metabolic Surgery

RecruitingPhase 4Healthy volunteers welcome
  • Indiana University, Indianapolis
Ages 18 to 75 · All sexes · Updated Jul 31, 2026 · NCT06374875

Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes

Recruiting
  • Indiana University, Indianapolis
Ages 18 to 45 · Women · Updated Jun 24, 2026 · NCT05124808

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.