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Healthy volunteer studies in San Francisco, CA

143 studies at sites in and around San Francisco accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women

RecruitingHealthy volunteers welcome
  • Alethios, San Francisco
Ages 25 to 45 · Women · Updated Sep 25, 2026 · NCT07831317

Comparison of Microbiome Changes in Healthy Adults Following Ketone Ester Consumption

RecruitingHealthy volunteers welcome
  • UCSF Wayne and Gladys Valley Center for Vision, San Francisco
Ages 18 to 40 · All sexes · Updated Sep 24, 2026 · NCT06954675

American Lung Association (ALA) Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 25 to 35 · All sexes · Updated Sep 23, 2026 · NCT04543461

Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study

RecruitingHealthy volunteers welcome
  • Zuckerberg Chan San Francisco General Hospital, San Francisco
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07557303

Ancillary Nocturnal Urinary Symptoms Analyses for TRIUMPH

RecruitingPhase 4Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 60 and older · Women · Updated Sep 22, 2026 · NCT07829029

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

RecruitingHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 30 to 74 · Women · Updated Sep 21, 2026 · NCT02620852

Inflammatory Challenge and Fear

RecruitingPhase 1Healthy volunteers welcome
  • San Francisco VA Health Care System, San Francisco
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06630884

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

RecruitingPhase 1Healthy volunteers welcome
  • Bridge HIV CRS, San Francisco
Ages 18 to 60 · All sexes · Updated Sep 18, 2026 · NCT06665646

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

RecruitingPhase 1Healthy volunteers welcome
  • University of California San Francisco (UCSF) Department of Neurology, San Francisco
Ages 65 to 85 · All sexes · Updated Sep 16, 2026 · NCT07516405

Lung and Heart Function Across Decades of Life in Health

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 24 to 68 · All sexes · Updated Sep 14, 2026 · NCT07641413

Safety Study of MucoCept-CVN

RecruitingPhase 1Healthy volunteers welcome
  • UCSF Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 to 45 · Women · Updated Sep 11, 2026 · NCT07181486

Near Infrared Spectroscopy (NIRS) for Assessment of Depression

RecruitingHealthy volunteers welcome
  • San Francisco Veterans Affairs Medical Center, San Francisco
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04061148

Trauma-Informed Care for Smoking Cessation for Pregnancy

RecruitingHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 and older · Women · Updated Sep 10, 2026 · NCT07129590

The Impact of Dietary Salt on the Severity of Eczema

RecruitingPhase 4Healthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco
  • UCSF Mt Zion Campus, San Francisco
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07447063

Observational, Non-Interventional Study Supporting Validation of eVO2peak Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05678530

A Study of Psychedelics in Healthy Older Adults With Low Well-being

RecruitingPhase 1Healthy volunteers welcome
  • University of California San Francisco, Sandler Neuroscience Building, San Francisco
Ages 50 to 85 · All sexes · Updated Sep 9, 2026 · NCT07386730

The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease

RecruitingPhase 4Healthy volunteers welcome
  • UCSF Mt Zion Campus, San Francisco
  • San Francisco VA Medical Center, San Francisco
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07487831

Inflammation, Diabetes, Ethnicity and Obesity Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT03022682

Parkinson Progression Marker Initiative Online (PPMI Online)

RecruitingObservational studyHealthy volunteers welcome
  • UCSF Movement Disorders and Neuromodulation Center (MDNC), San Francisco
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05065060

Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP

RecruitingEarly phase 1Healthy volunteers welcome
  • University of California, San Francisco/San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06414408

Assessing Brain Metabolism Using MRS With Deuterated Glucose

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06594315

UCSF Center for Genome Surgery Biobank and Registry

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
All ages · All sexes · Updated Sep 1, 2026 · NCT07396285

A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

RecruitingPhase 1Healthy volunteers welcome
  • Bridge HIV CRS (Site ID: 30305), San Francisco
Ages 18 to 55 · All sexes · Updated Sep 1, 2026 · NCT07390955

Women's Hormonal and Metabolic Wellbeing Study

RecruitingHealthy volunteers welcome
  • Alethios, Inc., San Francisco
Ages 18 to 45 · Women · Updated Aug 25, 2026 · NCT07268404

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

Enhancing Attention and Wellbeing Using Digital Therapeutics

RecruitingHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 60 to 99 · All sexes · Updated Aug 24, 2026 · NCT06397469

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

Dopamine and Sensorimotor Function in Stuttering

RecruitingPhase 1Healthy volunteers welcome
  • Biomagentic Imaging Lab, San Francisco
Ages 18 to 65 · All sexes · Updated Aug 19, 2026 · NCT07215884

Behavioral Safety and Fentanyl Education: BSAFE

RecruitingHealthy volunteers welcome
  • San Francisco Department of Public Health, San Francisco
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07219082

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

RecruitingPhase 1/2Healthy volunteers welcome
  • UCSF Community and Clinical Research Center, San Francisco
Ages 40 to 64 · All sexes · Updated Aug 18, 2026 · NCT06810934

Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER)

RecruitingObservational studyHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07770022

Evaluating the Impact of CONNECT in a Multilingual Population

RecruitingHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 50 to 80 · All sexes · Updated Aug 13, 2026 · NCT07111936

Sauna for Offline Connections and Interactive, Authentic Living

RecruitingHealthy volunteers welcome
  • Osher Center for Integrative Health, San Francisco
Ages 19 to 25 · All sexes · Updated Aug 13, 2026 · NCT07223099

Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

RecruitingObservational studyHealthy volunteers welcome
  • University of California-San Francisco, San Francisco
Ages 18 to 64 · Women · Updated Aug 11, 2026 · NCT06940323

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 6 and older · All sexes · Updated Aug 3, 2026 · NCT01060371

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

PSMA PET Combined With MRI for the Detection of PCa

RecruitingPhase 3Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

RecruitingHealthy volunteers welcome
  • UCSF Medical Center at Parnassus, San Francisco
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07087184

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco (UCSF), San Francisco
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Prescription of Letrozole for Uterine Myoma

RecruitingPhase 4Healthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 21 to 53 · Women · Updated Jul 22, 2026 · NCT06143631

Motiva Implants® Post-Approval Study

RecruitingHealthy volunteers welcome
  • Align Surgical Associates Inc, San Francisco
Ages 22 and older · Women · Updated Jul 17, 2026 · NCT06938399

Social Media Support Groups for Adolescent Vaping Cessation

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 13 and older · All sexes · Updated Jul 17, 2026 · NCT07540780

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
All ages · All sexes · Updated Jul 17, 2026 · NCT06259292

Sodium in the Skin and Atopic Dermatitis

RecruitingObservational studyHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco
  • UCSF Mt Zion Campus, San Francisco
Ages 50 and older · All sexes · Updated Jul 14, 2026 · NCT06998446

Cultural Adaptation of Drug Treatment for DJJ Youth

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 13 to 17 · All sexes · Updated Jul 13, 2026 · NCT06003725

CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

RecruitingObservational studyHealthy volunteers welcome
  • Alethios Digital Research Platform (Decentralized), San Francisco
Ages 18 to 65 · Women · Updated Jul 1, 2026 · NCT07679074

Childhood Cancer Survivor Study

RecruitingObservational studyHealthy volunteers welcome
  • University of California-San Francisco, San Francisco
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures

RecruitingHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 21 to 50 · All sexes · Updated Jun 16, 2026 · NCT06030674

Melanin and Dermal Uptake of Thirdhand Cigarette Smoke

RecruitingHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 to 50 · All sexes · Updated Jun 16, 2026 · NCT06020248

CONNECTing to LungCare

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT06213532

Naltrexone for Overdose Prevention

RecruitingPhase 2/3Healthy volunteers welcome
  • Center on Substance Use and Health, San Francisco
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT06633900

Village-Integrated Eye Worker Trial II

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 60 and older · All sexes · Updated Jun 9, 2026 · NCT03752840

Hyperpolarized Carbon Metabolic Imaging in Multiple Sclerosis

RecruitingPhase 2Healthy volunteers welcome
  • Byers Hall, San Francisco
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT07510607

Retinal Imaging in Patients With Inherited Retinal Degenerations

RecruitingObservational studyHealthy volunteers welcome
  • Department of Ophthalmology Retinal Degenerations Clinic, UCSF, San Francisco
Ages 13 and older · All sexes · Updated Jun 5, 2026 · NCT00254605

Lemborexant in Delayed Sleep Phase Syndrome

RecruitingPhase 4Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT06874855

Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy

RecruitingPhase 2Healthy volunteers welcome
  • UCSF Department of Plastic & Reconstructive Surgery, San Francisco
Ages 18 and older · Women · Updated Jun 4, 2026 · NCT05794321

Immune Spatial Features of Guselkumab Cutaneous Response

RecruitingPhase 4Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT05858632

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 15 to 55 · Women · Updated Jun 4, 2026 · NCT06030063

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

RecruitingPhase 2Healthy volunteers welcome
  • UCSF Mission Bay, San Francisco
Ages 21 to 70 · All sexes · Updated Jun 4, 2026 · NCT06626139

Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers

RecruitingObservational studyHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco
Ages 40 to 75 · All sexes · Updated Jun 4, 2026 · NCT04722835

Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT07049757

Multisite Implementation of COMPRENDO

RecruitingHealthy volunteers welcome
  • University of California San Francisco Benioff Children's Hospitals, San Francisco
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06055296

Glutide for Ending Methamphetamine

RecruitingPhase 2Healthy volunteers welcome
  • Center on Substance Use and Health, San Francisco
Ages 18 to 65 · All sexes · Updated Jun 3, 2026 · NCT07204249

SPIROMICS Study of Early COPD Progression (SOURCE)

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 30 to 55 · All sexes · Updated Jun 3, 2026 · NCT05033990

Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)

RecruitingEarly phase 1Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT07076862

Galleri® in the Medicare Population.

RecruitingHealthy volunteers welcome
  • University of California San Francisco Health System, San Francisco
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT05673018

Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT07418775

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

RecruitingPhase 1Healthy volunteers welcome
  • Zuckerberg San Francisco General Hospital (ZSFG), San Francisco
Ages 21 to 65 · All sexes · Updated May 14, 2026 · NCT05962229

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

RecruitingObservational studyHealthy volunteers welcome
  • UCSF Benioff Children's Hospital, San Francisco
Ages 3 to 17 · All sexes · Updated May 8, 2026 · NCT07573150

Wayfinding Intervention and Long-Term Memory

RecruitingHealthy volunteers welcome
  • UCSF Mission Bay, San Francisco
Ages 60 to 85 · All sexes · Updated May 7, 2026 · NCT05625425

Clinical and Biological Characteristics of Hidradenitis Suppurativa

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 13 and older · All sexes · Updated May 4, 2026 · NCT03967600

The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies

RecruitingObservational studyHealthy volunteers welcome
  • San Francisco General Hospital, San Francisco
Ages 18 to 70 · All sexes · Updated May 1, 2026 · NCT01202305

Efficacy and Safety of Shatavari Root Extract in Women's Sexual Wellness

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 20 to 50 · Women · Updated Apr 27, 2026 · NCT07441083

Effect of Ashwagandha Root Extract on Stress, Anxiety, and Sleep Quality in Adults Experiencing Minority Stress

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 18 to 45 · All sexes · Updated Apr 27, 2026 · NCT07441070

Mechanistic Insights From Bronchoscopy Airway Samples

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 to 70 · All sexes · Updated Apr 24, 2026 · NCT06105710

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

RecruitingHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Ages 18 to 75 · All sexes · Updated Apr 21, 2026 · NCT05780177

Glaucoma Screening to Enhance At-Risk Californians' Health

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 50 and older · All sexes · Updated Apr 15, 2026 · NCT06854198

Examining Olive Oil Extract on Knee Comfort and Function

RecruitingHealthy volunteers welcome
  • Alethios, Inc., San Francisco
Ages 40 to 75 · All sexes · Updated Apr 15, 2026 · NCT07514013

Collection of Blood for Multiple Collaborative Studies

RecruitingObservational studyHealthy volunteers welcome
  • San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT01336855

Optimizing Liver MRI Using Breath-Holding With and Without Oxygen

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 to 75 · All sexes · Updated Apr 13, 2026 · NCT07135401

Effera Dose Response: Women's Health

RecruitingHealthy volunteers welcome
  • Alethios, San Francisco
  • Alethios, Inc., San Francisco
Ages 18 to 40 · Women · Updated Apr 13, 2026 · NCT07524270

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

RecruitingPhase 3Healthy volunteers welcome
  • Regents of the University of California San Francisco, San Francisco
Ages 14 and older · Women · Updated Apr 9, 2026 · NCT06980025

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

RecruitingPhase 3Healthy volunteers welcome
  • Regents of the University of California San Francisco, San Francisco
All ages · Women · Updated Apr 9, 2026 · NCT06605118

Genomic Sequencing in Anatomically Normal Fetuses

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 to 64 · All sexes · Updated Apr 8, 2026 · NCT06211348

Decentralized Study to Evaluate a Dietary Supplement for Episodes of Mild Acute Stress in Healthy People

RecruitingHealthy volunteers welcome
  • Alethios (Virtual), San Francisco
Ages 18 to 60 · All sexes · Updated Apr 6, 2026 · NCT07511088

BID WM Digital Intervention in Aging

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 60 to 85 · All sexes · Updated Apr 1, 2026 · NCT06918704

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

RecruitingHealthy volunteers welcome
  • San Francisco State University, San Francisco
Ages 18 and older · All sexes · Updated Mar 25, 2026 · NCT07475702

TReating Incontinence for Underlying Mental and Physical Health

RecruitingPhase 4Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 60 and older · Women · Updated Mar 6, 2026 · NCT05362292

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

RecruitingHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco
Ages 21 to 85 · All sexes · Updated Mar 6, 2026 · NCT05265000

Chronic Infections and Inflammation in ME/CFS: An Observational Study

RecruitingObservational studyHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Mar 6, 2026 · NCT07227441

Multidisciplinary Low-Barrier and Mobile HIV Care to Improve Retention and Viral Suppression: Stakeholder-Engaged Design and Evaluation

RecruitingHealthy volunteers welcome
  • San Francisco AIDS Foundation, San Francisco
  • San Francisco Department of Public Health Maria X Martinez Clinic, San Francisco
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 15 and older · All sexes · Updated Feb 24, 2026 · NCT05887557

An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 18 to 80 · All sexes · Updated Feb 24, 2026 · NCT07421596

Fiber and Calcium Absorption in Older Men

RecruitingPhase 2Healthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Ages 60 and older · Men · Updated Feb 17, 2026 · NCT06519877

The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain

RecruitingHealthy volunteers welcome
  • University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco
Ages 12 and older · All sexes · Updated Feb 17, 2026 · NCT06573996

The ROAR Study: Reactive Oxygen Species and Reproduction

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 to 43 · All sexes · Updated Feb 17, 2026 · NCT06831019

Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)

RecruitingHealthy volunteers welcome
  • Alethios, Inc., San Francisco
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT07407777

A Study of a Dietary Supplement on Serum Biomarkers in Children

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 4 to 15 · All sexes · Updated Feb 4, 2026 · NCT07385144

Role of Transposable Elements in Septic Immune Aging

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jan 30, 2026 · NCT06809868

Efficacy of Repeated Low-level Red-light Therapy in Myopia Control

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 8 to 13 · All sexes · Updated Jan 28, 2026 · NCT05606237

Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairment and Insulin Resistance

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 40 to 80 · All sexes · Updated Jan 28, 2026 · NCT07220694

Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

RecruitingHealthy volunteers welcome
  • University of California San Francisco Fetal Treatment Center, San Francisco
Ages 18 and older · Women · Updated Jan 28, 2026 · NCT04583644

Patient-centered Information on Permanent Contraception

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 21 to 45 · Women · Updated Jan 26, 2026 · NCT06296797

Direct-to-patient Teledermatology and Computer-assisted Diagnosis

RecruitingObservational studyHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT05128006

This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction

RecruitingPhase 2Healthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06853223

@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT05526352

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

RecruitingPhase 3Healthy volunteers welcome
  • Kaiser Permanente-San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jan 13, 2026 · NCT05006482

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

RecruitingPhase 2Healthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 21 to 65 · All sexes · Updated Jan 7, 2026 · NCT05999383

Accuracy Evaluation of the Owlet OSS 3.0-M1 Sensor in Toddlers and Preschoolers

RecruitingHealthy volunteers welcome
  • Vital Signs Research Group, LLC, San Francisco
19 Months – 60 Months · All sexes · Updated Jan 7, 2026 · NCT07321938

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

RecruitingPhase 1Healthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Dec 29, 2025 · NCT06522932

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

RecruitingHealthy volunteers welcome
  • Pacific Rims Optometry, San Francisco
Ages 6 to 8 · All sexes · Updated Dec 29, 2025 · NCT06034327

Precision Dosing of Metformin in Youth With T2D

RecruitingEarly phase 1Healthy volunteers welcome
  • UCSF Benioff Children's Hospital San Francisco, Madison Clinic for Pediatric Diabetes, San Francisco
Ages 10 to 21 · All sexes · Updated Dec 23, 2025 · NCT06120881

Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT06774027

Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing

RecruitingHealthy volunteers welcome
  • Mercy Housing, San Francisco
  • Delivering Innovation in Supportive Housing (DISH), San Francisco
  • Episcopal Community Services, San Francisco
  • and 1 more
Ages 50 and older · All sexes · Updated Nov 20, 2025 · NCT06239896

Mirai-MRI: Validation of AI Models for Breast Cancer Risk

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 40 to 89 · Women · Updated Nov 6, 2025 · NCT07121972

ChangeGradients: Promoting Adolescent Health Behavior Change

RecruitingHealthy volunteers welcome
  • University of California San Francisco Adolescent and Young Adult Medicine Clinic, San Francisco
Ages 15 to 17 · All sexes · Updated Oct 31, 2025 · NCT04110756

SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
All ages · All sexes · Updated Oct 24, 2025 · NCT04885179

A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

RecruitingObservational studyHealthy volunteers welcome
  • University of California, San Francisco
Up to age 16 · All sexes · Updated Oct 23, 2025 · NCT06354699

Effects of KSM-66 Ashwagandha® (300 mg) on Skin and Hair Health in Healthy Men and Women"

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 18 to 60 · All sexes · Updated Oct 15, 2025 · NCT07215689

Smoking Cessation CM for Veterans With or at Risk for Cancer

RecruitingHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Ages 18 and older · All sexes · Updated Sep 30, 2025 · NCT06432985

A Study to Evaluate Community-Based Measures to Increase RSV Vaccine Use Among Latino Adults

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 30, 2025 · NCT07171164

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

RecruitingPhase 1Healthy volunteers welcome
  • Bridge HIV, San Francisco Department of Public Health, San Francisco
Ages 18 to 55 · All sexes · Updated Sep 25, 2025 · NCT06796686

The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots

RecruitingHealthy volunteers welcome
  • Amazentis USA, San Francisco
Ages 18 to 80 · All sexes · Updated Sep 8, 2025 · NCT04985630

Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

RecruitingObservational studyHealthy volunteers welcome
  • Hypoxia Lab, UCSF Department of Anesthesia and Perioperative Care, San Francisco
Ages 18 to 50 · All sexes · Updated Sep 2, 2025 · NCT06142019

Medial-prefrontal Enhancement During Schizophrenia Systems Imaging

RecruitingHealthy volunteers welcome
  • UCSF, San Francisco
Ages 18 to 64 · All sexes · Updated Aug 29, 2025 · NCT04807530

EyeConic: Qualification for Cone-Optogenetics

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, Department of Ophthalmology, San Francisco
All ages · All sexes · Updated Jul 31, 2025 · NCT05294978

A Randomized, Double Blind, Placebo Controlled, Clinical Study to Examine the Benefits of an Oral Product in Panelists With Menopausal Symptoms Including Vasomotor Symptoms (VMS).

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 40 to 65 · Women · Updated Jul 16, 2025 · NCT07033013

Comparison of Methods for Recording Post Operative Pain

RecruitingHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Jul 14, 2025 · NCT06206148

TrialNet Pathway to Prevention of T1D

RecruitingObservational studyHealthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 2 to 45 · All sexes · Updated Jul 1, 2025 · NCT00097292

PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)

RecruitingPhase 1Healthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 5, 2025 · NCT03729752

Valacyclovir in Pain Management of Acute Apical Abscesses

RecruitingPhase 2Healthy volunteers welcome
  • UCSF Dental, San Francisco
Ages 18 to 80 · All sexes · Updated May 30, 2025 · NCT05266040

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

RecruitingPhase 1/2Healthy volunteers welcome
  • UCSF, San Francisco
Ages 18 to 80 · All sexes · Updated May 2, 2025 · NCT05395624

First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

RecruitingPhase 1/2Healthy volunteers welcome
  • China Basin, UCSF, San Francisco
Ages 40 to 75 · All sexes · Updated Apr 17, 2025 · NCT05374278

Spermatogonial Differentiation Via Testicular Organoid

RecruitingPhase 1/2Healthy volunteers welcome
  • The Turek Clinic, San Francisco
Ages 18 to 60 · Men · Updated Feb 24, 2025 · NCT06841861

Smoke-free Home Study in Subsidized Housing

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Feb 24, 2025 · NCT06170437

Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas

RecruitingPhase 3Healthy volunteers welcome
  • UCSF Imaging Center, San Francisco
Ages 8 and older · All sexes · Updated Feb 19, 2025 · NCT02923011

Efficacy and Safety of Shatavari for Treatment of Menopausal Symptoms in Women: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

RecruitingHealthy volunteers welcome
  • SF Research Institute, Inc., San Francisco
Ages 45 to 55 · Women · Updated Dec 4, 2024 · NCT06716554

Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

RecruitingHealthy volunteers welcome
  • San Francisco Research Institute, San Francisco
Ages 18 to 65 · All sexes · Updated Dec 4, 2024 · NCT06714942

PrEPsmart 2-1-1 Pilot

RecruitingPhase 2Healthy volunteers welcome
  • Bridge HIV, San Francisco Department of Public Health, San Francisco
Ages 18 and older · Men · Updated Oct 8, 2024 · NCT06631365

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of California - San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention

RecruitingHealthy volunteers welcome
  • San Francisco AIDS Foundation, San Francisco
Ages 15 and older · All sexes · Updated Sep 28, 2022 · NCT04855773

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.