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Heart Failure clinical trials in Boston, MA
44 studies for Heart Failure are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.
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ELEVATE-HFpEF Clinical Study
Recruiting
- Tufts Medical Center, Boston
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
RecruitingPhase 3
- Research Site, Boston
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
- Boston Medical Center, Boston
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
RecruitingObservational studyHealthy volunteers welcome
- Mass General Brigham, Boston
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
RecruitingObservational studyHealthy volunteers welcome
- Mass General Brigham, Boston
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
RecruitingPhase 3
- Research Site, Boston
- Research Site, Boston
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
RecruitingPhase 3
- Tufts Medical Center, Boston
Alleviant ALLAY-HFrEF Study
Recruiting
- Tufts Medical Center, Boston
- Brigham and Women's Hospital, Boston
- Boston Medical Center, Boston
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
RecruitingPhase 3
- Research Site, Boston
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
RecruitingPhase 3
- Boston, MA Investigative Stie 10087, Boston
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Recruiting
- Tufts Medical Center, Boston
- Massachusetts General Hospital, Boston
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Recruiting
- Massachusetts General Hospital, Boston
Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)
Recruiting
- Mass General Brigham, Boston
Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Hospital, Boston
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
RecruitingPhase 2/3
- Boston Children's Hospital ( Site 0035), Boston
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
RecruitingPhase 2
- Massachusetts General Hospital, Boston
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
RecruitingObservational study
- Research Site, Boston
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- Boston, Boston
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- Harvard (Massachusetts General Hospital), Boston
- Harvard Medical School - Brigham and Women's Hospital (BWH), Boston
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
RecruitingPhase 3
- Tenax Investigational Site, Boston
Alleviant ALLAY-HF Study
Recruiting
- Brigham and Women's Hospital, Boston
- Boston Medical Center, Boston
OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
RecruitingObservational study
- Tufts Medical Center, Boston
Assessment of CCM in HF With Higher Ejection Fraction
Recruiting
- Massachusetts General Hospital, Boston
Care Transitions App for Patients With Multiple Chronic Conditions
RecruitingHealthy volunteers welcome
- Brigham and Women's Hospital, Boston
The STOP-MED CTRCD Trial
RecruitingPhase 4
- Brigham and Women's Hospital, Boston
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Boston Children's Hospital - Main Campus - Cardiology, Boston
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
- Tufts Medical Center, Boston
- Boston Medical Center Corporation, Boston
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Boston Children's Hospital - Main Campus - Cardiology, Boston
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
- Massachusetts General Hospital, Boston
CCM OPEN HF Registry
RecruitingObservational study
- Massachusetts General Hospital, Boston
Promoting Well-being and Health in Heart Failure
Recruiting
- Massachusetts General Hospital, Boston
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- St Elizabeth's Medical Center, Boston
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess, Boston
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
RecruitingPhase 3
- Joslin Diabetes Center, Boston
Home Hospital for Suddenly Ill Adults
Recruiting
- Brigham and Women's Hospital, Boston
- Brigham and Women's Faulkner Hospital, Boston
Diffusion MRI in Heart Failure
RecruitingEarly phase 1Healthy volunteers welcome
- Massachusetts General Hospital, Charlestown · 1 mi away
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure
Recruiting
- Tufts Medical Center, Boston
Pulmonary Artery Catheter in Cardiogenic Shock Trial
Recruiting
- Tufts Medical Center, Boston
US Benchmarking Clinical Study
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Hospital, Boston
- Brigham and Women's Hospital, Boston
- Boston Medical Center, Boston
Left vs Left Randomized Clinical Trial
Recruiting
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
Cardiogenic Shock Working Group Registry
RecruitingObservational study
- Tufts Medical Center, Boston
- Beth Israel Deaconess Medical Center, Boston
A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System
Recruiting
- One Boston Medical Center Place, Boston
Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure
RecruitingObservational study
- Tufts Medical Center, Boston
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
RecruitingPhase 1
- Brigham and Women's Hospital, Boston
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
RecruitingObservational study
- Brigham and Women's Hospital, Boston
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- New York City, NY51 studies
- Dallas, TX42 studies
- Houston, TX36 studies
- Cleveland, OH33 studies
- Chicago, IL31 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- St. Louis, MO26 studies
- Durham, NC26 studies
- Kansas City, MO25 studies
- Atlanta, GA25 studies
- Baltimore, MD24 studies
Other studies in Boston
- Breast Cancer111 studies
- Non-Small Cell Lung Cancer90 studies
- Cancer (all types)86 studies
- Colorectal Cancer63 studies
- Metastatic Cancer63 studies
- Lung Cancer62 studies
- Ovarian Cancer61 studies
- Prostate Cancer59 studies
- Depression52 studies
- Endometrial Cancer50 studies
- Acute Myeloid Leukemia44 studies
- Pancreatic Cancer43 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.