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Healthy volunteer studies in Philadelphia, PA

197 studies at sites in and around Philadelphia accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Dental Implant Healing With TNF-Alpha Inhibitors

RecruitingHealthy volunteers welcomeMentions payment for participants
  • University of Pennsylvania School of Dental Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06538870

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
  • Children's Hospital of Philadelphia, Philadelphia
1 Month – 100 Years · All sexes · Updated Oct 2, 2026 · NCT02450851

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

RecruitingHealthy volunteers welcome
  • Christiana Care Health System-Concord Health Center, Chadds Ford · 23 mi away
  • Christiana Care Health System-Wilmington Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07283939

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Reading Hospital McGlinn Cancer Institute at Phoenixville, Phoenixville · 22 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 5 and older · All sexes · Updated Oct 2, 2026 · NCT02544022

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Alfred I duPont Hospital for Children, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

RecruitingObservational studyHealthy volunteers welcome
  • Decentralized / At-Home Participation (U.S.), Philadelphia
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07775495

Blinatumomab Consolidation in Real World

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07117136

A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease

RecruitingPhase 1Healthy volunteers welcome
  • University of Pennsylvania, Dept of Neurology, Philadelphia
Ages 30 to 80 · All sexes · Updated Oct 1, 2026 · NCT06565195

Empathic Communication Skills (ECS) Training

RecruitingHealthy volunteers welcome
  • University of Pennsylvania (Data Collection Only), Philadelphia
  • Fox Chase Cancer Center (Data Collection Only), Philadelphia
Ages 18 to 100 · All sexes · Updated Oct 1, 2026 · NCT05456841

A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects

RecruitingPhase 4Healthy volunteers welcome
  • Shafer Vision Institute, Plymouth Meeting · 12 mi away
Ages 40 and older · All sexes · Updated Sep 30, 2026 · NCT06922084

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT06517186

HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634

A Prospective Natural History Study of Lymphatic Anomalies

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
1 Day – 100 Years · All sexes · Updated Sep 28, 2026 · NCT05731141

Developing New Ways to Detect Respiratory Impairment Early in ALS

RecruitingObservational studyHealthy volunteers welcome
  • Thomas Jefferson University - Center City, Philadelphia
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07844590

A Study of COVID-19 Vaccine(s) in Children and Adults

RecruitingPhase 3Healthy volunteers welcome
  • DM Clinical Research, Philadelphia
Ages 5 and older · All sexes · Updated Sep 28, 2026 · NCT07798648

Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)

RecruitingObservational studyHealthy volunteers welcome
  • 3400 Civic Center Blvd, Philadelphia
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT05865054

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • DM Clinical Research - Philadelphia- Site Number : 8400046, Philadelphia
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

RecruitingPhase 1Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 45 · All sexes · Updated Sep 24, 2026 · NCT03721822

American Lung Association (ALA) Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 25 to 35 · All sexes · Updated Sep 23, 2026 · NCT04543461

Phenotyping Genetic Risk for Type 2 Diabetes

RecruitingHealthy volunteers welcome
  • Childrens Hospital of Philadelphia, Philadelphia
  • University of Pennsylvania, Philadelphia
Ages 10 to 70 · All sexes · Updated Sep 21, 2026 · NCT04024631

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

RecruitingPhase 3Healthy volunteers welcome
  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT07218354

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

RecruitingPhase 3Healthy volunteers welcome
  • Pennsylvania College of Optometry at Drexel University, Elkins Park · 9 mi away
Ages 6 to 11 · All sexes · Updated Sep 21, 2026 · NCT07567040

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

RecruitingPhase 3Healthy volunteers welcome
  • Perelman Center for Advance Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05456503

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Philadelphia
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

RecruitingPhase 1Healthy volunteers welcome
  • Penn Prevention CRS (Site ID# 30310), Philadelphia
Ages 18 to 60 · All sexes · Updated Sep 18, 2026 · NCT06665646

A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

RecruitingPhase 1Healthy volunteers welcome
  • St Christopher Hosp for Child, Philadelphia
Ages 18 to 64 · Men · Updated Sep 18, 2026 · NCT07220564

Cholate Clearance in Fontan and Heart Failure

RecruitingObservational studyHealthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07009132

Natural History Study of Mitochondrial Myopathy

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 0 to 100 · All sexes · Updated Sep 17, 2026 · NCT05250375

Validation of NAD+ Measurements for Human Clinical Studies

RecruitingHealthy volunteers welcome
  • Penn Medicine, Philadelphia
Ages 18 to 110 · All sexes · Updated Sep 11, 2026 · NCT07416786

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Philadelphia
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Medical Residents Learning Weight Management Counseling Skills

RecruitingHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06529666

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

RecruitingPhase 3Healthy volunteers welcome
  • DM Clinical Research - Philadelphia, Philadelphia
Ages 65 and older · All sexes · Updated Sep 9, 2026 · NCT07282665

Observational, Non-Interventional Study Supporting Validation of eVO2peak Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Cardiac Center, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05678530

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Childrens Hospital Of Philadelphia, Philadelphia
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

Li-Fraumeni Syndrome/TP53 Biobank

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Sep 4, 2026 · NCT04367246

Quality of End-of-Life Care for Children With Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Alfred I duPont Hospital for Children, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07412002

BCAAs in Concussion 3.0

RecruitingPhase 2Healthy volunteers welcome
  • Children's Hospital of Philadelphia, Havertown · 8 mi away
Ages 11 to 23 · All sexes · Updated Sep 3, 2026 · NCT07670195

Biofluid Research on Age-Related or Inherited Neurodegeneration

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798700

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
All ages · All sexes · Updated Sep 1, 2026 · NCT06016946

A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

RecruitingPhase 1Healthy volunteers welcome
  • Penn Prevention CRS (Site ID: 30310), Philadelphia
Ages 18 to 55 · All sexes · Updated Sep 1, 2026 · NCT07390955

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Pilot Implementation Trial of Implementation Toolkits for Diabetes Coaching

RecruitingHealthy volunteers welcome
  • Nemours Children's Hospital - Delaware, Wilmington · 25 mi away
All ages · All sexes · Updated Aug 27, 2026 · NCT07766811

Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation

RecruitingHealthy volunteers welcome
  • Childrens Hospital of Philadelphia, Philadelphia
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07778823

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
  • Temple University, Philadelphia
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

tACS to Enhance Language Abilities

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 85 · All sexes · Updated Aug 24, 2026 · NCT06092814

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

RecruitingHealthy volunteers welcome
  • Wills Eye Glaucoma Service, Philadelphia
Ages 18 to 90 · All sexes · Updated Aug 20, 2026 · NCT03675412

Evaluation of Filler Injection for Chin Profile Enhancement

RecruitingPhase 4Healthy volunteers welcome
  • Penn Medicine, Philadelphia
Ages 22 to 55 · All sexes · Updated Aug 20, 2026 · NCT07777926

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

RecruitingPhase 4Healthy volunteers welcome
  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
  • Philadelphia MultiService Center, Philadelphia, PA, Philadelphia
Ages 40 and older · All sexes · Updated Aug 19, 2026 · NCT04373317

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Local Institution - 0029, Philadelphia
  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 16 and older · All sexes · Updated Aug 14, 2026 · NCT07246057

Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma

RecruitingEarly phase 1Healthy volunteers welcome
  • Abramson Cancer Center at University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05733715

Improving Care Transitions for Medicaid Insured Individuals With Co-occurring Serious Mental Illness

RecruitingHealthy volunteers welcome
  • Upenn School of Nursing Centre For Health Outcomes Policy Research, Philadelphia
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06203509

PopSci CHW4CervixHealth

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 25 to 65 · Women · Updated Aug 11, 2026 · NCT07336134

DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention

RecruitingHealthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
  • Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07698483

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT00288119

Shield Post-Approval Study Protocol

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055

Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

RecruitingPhase 1Healthy volunteers welcome
  • Penn Prevention CRS (Site ID 30310), Philadelphia
Ages 18 to 55 · All sexes · Updated Aug 6, 2026 · NCT07390474

Neurobehavioral Changes Following Spaceflight Stressors

RecruitingHealthy volunteers welcome
  • University of Pennsylvania Perelman School of Medicine, Philadelphia
Ages 21 to 60 · All sexes · Updated Aug 6, 2026 · NCT07293494

18F-FTHA IMAGING OF THE INTESTINAL AND CENTRAL LYMPHATIC SYSTEM

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07645573

Healthy Volunteers Enteral Nutrition Study (HEN)

RecruitingHealthy volunteers welcome
  • Penn Center for Advance Medicine, University of Pennsylvania, Philadelphia
Ages 18 to 70 · All sexes · Updated Aug 6, 2026 · NCT07426003

Effects of Ketogenic Diet on Alcohol Intoxication

RecruitingHealthy volunteers welcome
  • Center for Studies of Addiction, Philadelphia
Ages 21 to 50 · All sexes · Updated Aug 4, 2026 · NCT07602270

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 6 and older · All sexes · Updated Aug 3, 2026 · NCT01060371

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

RecruitingHealthy volunteers welcome
  • University of Pennsylvania/Abramson Cancer Center, Philadelphia
Ages 25 and older · Women · Updated Jul 31, 2026 · NCT07281430

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University Hospital, Philadelphia
Ages 45 to 74 · Women · Updated Jul 31, 2026 · NCT05625659

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

PSMA PET Combined With MRI for the Detection of PCa

RecruitingPhase 3Healthy volunteers welcome
  • MidLantic Urology, Philadelphia
Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

RecruitingPhase 1Healthy volunteers welcome
  • Paddington Testing Company, Philadelphia
Ages 18 to 70 · All sexes · Updated Jul 22, 2026 · NCT06564389

Examining the Efficacy of the PRAISE With Coaching Program

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 8 and older · All sexes · Updated Jul 22, 2026 · NCT07191782

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Non-Invasive Preeclampsia Screening and Biobank

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania Perelman School of Medicine, Philadelphia
  • Lewis Katz School of Medicine at Temple University, Philadelphia
Ages 18 and older · Women · Updated Jul 20, 2026 · NCT06643741

UnityPhilly Response App for Overdose Reversal

RecruitingHealthy volunteers welcome
  • Drexel University, Philadelphia
Ages 18 and older · All sexes · Updated Jul 20, 2026 · NCT06466005

An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

RecruitingHealthy volunteers welcome
  • Drexel University, Philadelphia
Ages 14 to 19 · Women · Updated Jul 20, 2026 · NCT06147973

Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

RecruitingHealthy volunteers welcome
  • Nemours Children's Health, Delaware, Wilmington · 25 mi away
All ages · All sexes · Updated Jul 17, 2026 · NCT05294302

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Jul 17, 2026 · NCT06259292

Health-E You Efficacy Trial for Male Adolescents

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 13 to 21 · Men · Updated Jul 15, 2026 · NCT06525064

Intervention to Improve Parent Communication About Sexuality

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 12 to 100 · All sexes · Updated Jul 15, 2026 · NCT07672067

Fiber Food Introduction in Pediatric Short Bowel Syndrome

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
4 Months – 18 Years · All sexes · Updated Jul 10, 2026 · NCT05432648

Autobiographical Memory in Opioid Use Disorder

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 60 · All sexes · Updated Jul 10, 2026 · NCT06643988

An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)

RecruitingHealthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
  • Penn Center for Women's Behavioral Wellness, Philadelphia
  • Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06576323

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

RecruitingPhase 1Healthy volunteers welcome
  • Perelman Center for Advanced Medicine (PCAM)- Penn Blood Disorders Program, Philadelphia
Ages 18 to 60 · All sexes · Updated Jul 2, 2026 · NCT06349473

Molecular Genetics Studies of Cancer Patients and Their Relatives

RecruitingObservational studyHealthy volunteers welcome
  • Paoli Memorial Hospital, Paoli · 18 mi away
All ages · All sexes · Updated Jun 29, 2026 · NCT04185935

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Oropharyngeal Candidiasis (OPC) and S-ECC

RecruitingObservational studyHealthy volunteers welcome
  • Temple University, Philadelphia
9 Months – 15 Months · All sexes · Updated Jun 22, 2026 · NCT05761197

Childhood Cancer Survivor Study

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 21 and older · All sexes · Updated Jun 11, 2026 · NCT07199517

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

RecruitingPhase 1/2Healthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 12 to 85 · All sexes · Updated Jun 11, 2026 · NCT04959175

Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Jun 8, 2026 · NCT06930417

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

RecruitingHealthy volunteers welcome
  • Sago Philadelphia, Philadelphia
Ages 21 to 65 · All sexes · Updated Jun 3, 2026 · NCT07598136

SPIROMICS Study of Early COPD Progression (SOURCE)

RecruitingObservational studyHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 30 to 55 · All sexes · Updated Jun 3, 2026 · NCT05033990

LATe Cerclage in High-risk Pregnancies (LATCH)

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 18 to 50 · Women · Updated May 29, 2026 · NCT06036446

Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

RecruitingHealthy volunteers welcome
  • Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
Ages 50 to 77 · All sexes · Updated May 29, 2026 · NCT05679349

Optimizing a Mobile Health Platform for Sleep Promotion and Obesity Prevention in Children

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 8 to 12 · All sexes · Updated May 27, 2026 · NCT05703347

Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)

RecruitingObservational studyHealthy volunteers welcome
  • Penn Medicine; Perelman School of Medicine, Philadelphia
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT07548099

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Center for Preventive Ophthalmology and Biostatistics, Philadelphia
All ages · All sexes · Updated May 22, 2026 · NCT04995341

Click & Pick Study

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07422922

The Collaborative Care PrTNER Study

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 15 to 29 · Men · Updated May 18, 2026 · NCT06585631

Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs

RecruitingObservational studyHealthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 18 and older · Women · Updated May 15, 2026 · NCT07038785

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania/Abramson Cancer Center, Philadelphia
Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network

RecruitingObservational studyHealthy volunteers welcome
  • Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
Ages 18 and older · Men · Updated May 15, 2026 · NCT05627219

Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT07042347

A Study to Learn About mRNA Vaccines Against Influenza in Adults

RecruitingPhase 2Healthy volunteers welcome
  • DM Clinical Research - Philadelphia, Philadelphia
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07431853

Variability in Analgesic Response to Ibuprofen

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania School of Dental Medicine, Philadelphia
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06539741

High Resolution Retinal Imaging

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 7 and older · All sexes · Updated May 5, 2026 · NCT01866371

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

RecruitingPhase 2Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 50 to 90 · All sexes · Updated May 5, 2026 · NCT05386394

Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
18 Months – 99 Years · All sexes · Updated May 1, 2026 · NCT05233150

Acellular Dermal Matrix Investigation in Breast Reconstruction

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 22 and older · Women · Updated Apr 30, 2026 · NCT06456554

A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis

RecruitingPhase 1Healthy volunteers welcome
  • Sitryx Clinical Site, Philadelphia
Ages 18 to 65 · All sexes · Updated Apr 30, 2026 · NCT07558668

Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 40 to 85 · All sexes · Updated Apr 24, 2026 · NCT06303921

B.Brilliant Revelation Comparision Study

RecruitingObservational studyHealthy volunteers welcome
  • Pennsylvania Hospital, Center for Breast Imaging, Philadelphia
Ages 18 and older · Women · Updated Apr 24, 2026 · NCT07067788

Rezdiffra Pregnancy and Lactation Registry

RecruitingObservational studyHealthy volunteers welcome
  • Madrigal Pharmaceuticals, West Conshohocken · 11 mi away
All ages · Women · Updated Apr 21, 2026 · NCT07541469

Enriched Holistic Care to Eradicate Disparities in Maternal Morbidity

RecruitingHealthy volunteers welcome
  • Pennsylvania Hospital, Philadelphia
Ages 16 to 55 · Women · Updated Apr 21, 2026 · NCT06245057

A Global Study of the PETAL Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06067347

Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

RecruitingPhase 3Healthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
All ages · Women · Updated Apr 9, 2026 · NCT06605118

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

RecruitingPhase 3Healthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 14 and older · Women · Updated Apr 9, 2026 · NCT06980025

DILIN - Prospective Study

RecruitingObservational studyHealthy volunteers welcome
  • Thomas Jefferson, Philadelphia
Ages 2 and older · All sexes · Updated Apr 8, 2026 · NCT00345930

Urinary Titin Biomarker in DMD

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 2 to 10 · Men · Updated Apr 8, 2026 · NCT07332013

Driver Education Research Study

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 16 to 17 · All sexes · Updated Apr 6, 2026 · NCT06413927

Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

RecruitingObservational studyHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 to 85 · All sexes · Updated Apr 3, 2026 · NCT04661215

RemI for Post-Bariatric Surgery Weight Regain

RecruitingHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 to 70 · All sexes · Updated Apr 3, 2026 · NCT06292936

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Christiana Care Health System-Concord Health Center, Chadds Ford · 23 mi away
  • Christiana Care Health System-Wilmington Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Longitudinal Assessment of Traumatic Microvascular Injury-2

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 65 · All sexes · Updated Mar 31, 2026 · NCT05725993

Effects of Ketone Supplement and Alcohol on Brain Metabolism

RecruitingPhase 2/3Healthy volunteers welcome
  • Center for Studies of Addiction, Philadelphia
Ages 21 to 65 · All sexes · Updated Mar 25, 2026 · NCT06815237

Neonatal Platelet Transfusion Threshold Trial

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
1 Hour – 48 Hours · All sexes · Updated Mar 25, 2026 · NCT06676904

Eatwell Clinical Trial (R01)

RecruitingHealthy volunteers welcome
  • Drexel University, Philadelphia
Ages 18 and older · All sexes · Updated Mar 16, 2026 · NCT07225881

Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)

RecruitingObservational studyHealthy volunteers welcome
  • Abramson Cancer Center at the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT07471958

Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 21 and older · All sexes · Updated Mar 12, 2026 · NCT06372899

Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study

RecruitingHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 to 25 · All sexes · Updated Mar 6, 2026 · NCT06804109

Transformative Research in Diabetic Nephropathy 2.0

RecruitingObservational studyHealthy volunteers welcome
  • Penn Presbyterian Medical Center, Philadelphia
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT07444203

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 21 and older · All sexes · Updated Feb 19, 2026 · NCT06264154

Validation of Oxygen Nanosensor in Mitochondrial Myopathy

RecruitingPhase 1Healthy volunteers welcome
  • The Children's Hospital of Philadelphia, Philadelphia
Ages 18 to 65 · All sexes · Updated Feb 18, 2026 · NCT04086329

Validation of Nanosensor Oxygen Measurement

RecruitingPhase 1Healthy volunteers welcome
  • The Children's Hospital of Philadelphia, Philadelphia
Ages 18 to 65 · All sexes · Updated Feb 17, 2026 · NCT06819683

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal

RecruitingPhase 2Healthy volunteers welcome
  • University of Pennsylvania, Treatment Research Center, Philadelphia
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT05995535

Localizing Epileptic Networks Using MRI and iEEG

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT04649008

BSGM to Evaluate Patients With GI Symptoms

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 8 to 25 · All sexes · Updated Feb 10, 2026 · NCT05880199

Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults

RecruitingPhase 4Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT05108818

Ketone Ester Intervention in Alcohol Use Disorder

RecruitingPhase 2/3Healthy volunteers welcome
  • University of Pennsylvania Center for Studies of Addiction, Philadelphia
Ages 21 to 65 · All sexes · Updated Feb 9, 2026 · NCT04616781

Neurometabolic Profile of Individuals With Primary Mitochondrial Disease

RecruitingObservational studyHealthy volunteers welcome
  • The Children's Hospital of Philadelphia, Philadelphia
Ages 8 to 75 · All sexes · Updated Feb 5, 2026 · NCT06890520

Healthy Volunteers Study

RecruitingObservational studyHealthy volunteers welcome
  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
Ages 30 to 50 · Women · Updated Feb 5, 2026 · NCT06962059

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

RecruitingObservational studyHealthy volunteers welcome
  • The Children's Hospital of Philadelphia, Philadelphia
All ages · All sexes · Updated Feb 4, 2026 · NCT01694940

Cervical Ripening as an Outpatient Method Using the Foley (COMFORT)

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 60 · Women · Updated Feb 2, 2026 · NCT05759988

UPenn Observational Research Repository on Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT04715399

Maternal Newborn Health Registry

RecruitingObservational studyHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
All ages · All sexes · Updated Jan 21, 2026 · NCT01073475

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

RecruitingHealthy volunteers welcome
  • Abramson Cancer Center at the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT05427240

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jan 14, 2026 · NCT01851694

Menstrual Cycle TMS Plasticity Pilot

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 20 to 40 · All sexes · Updated Jan 9, 2026 · NCT07180654

Resting State Changes Following Theta Burst Stimulation

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 60 · All sexes · Updated Jan 7, 2026 · NCT05322239

Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Jan 7, 2026 · NCT06510894

CW2IP2: Imaging and Diagnostic Assessments

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 40 to 85 · All sexes · Updated Jan 7, 2026 · NCT06083467

CARE Study: Cancer, Asian Americans, and Relationship Enrichment

RecruitingHealthy volunteers welcome
  • Fox Chase Cancer Center - Philadelphia, Philadelphia
Ages 21 to 80 · All sexes · Updated Dec 31, 2025 · NCT06782581

CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · Women · Updated Dec 23, 2025 · NCT06957028

A Study of Emapalumab for Pediatric Aplastic Anemia

RecruitingPhase 2Healthy volunteers welcome
  • Children's Hospital of Philadelphia (Data Collection AND Specimen Analysis), Philadelphia
Ages 0 to 25 · All sexes · Updated Dec 17, 2025 · NCT06430788

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

RecruitingObservational studyHealthy volunteers welcome
  • The Eye Institute, Philadelphia
Ages 18 to 35 · All sexes · Updated Dec 15, 2025 · NCT07282691

Diet and Motility in IBS

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 8 to 18 · All sexes · Updated Dec 15, 2025 · NCT07283341

Non-Invasive Respiratory Monitor

RecruitingHealthy volunteers welcome
  • Nemours/A.I. duPont Hospital for Children, Wilmington · 25 mi away
Ages 11 to 17 · All sexes · Updated Nov 21, 2025 · NCT02851043

Imaging Assessments of ARPKD Kidney Disease Progression

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 6 and older · All sexes · Updated Nov 21, 2025 · NCT07201025

Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 40 to 80 · All sexes · Updated Nov 19, 2025 · NCT06032026

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

RecruitingObservational studyHealthy volunteers welcome
  • Shady Grove Fertility, Chesterbrook · 18 mi away
All ages · All sexes · Updated Nov 12, 2025 · NCT07227116

Applying pGz in Mitochondrial Disease

RecruitingPhase 1Healthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 10 to 60 · All sexes · Updated Nov 10, 2025 · NCT05569122

Collection of Samples USOPTIVAL Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 45 to 84 · All sexes · Updated Nov 10, 2025 · NCT04792684

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Children's Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Nov 6, 2025 · NCT06071377

Nurturing Needs Study: Parenting Food Motivated Children

RecruitingHealthy volunteers welcome
  • Temple University - Center for Obesity Research and Education, Philadelphia
Ages 4 to 5 · All sexes · Updated Nov 5, 2025 · NCT06111040

Food Genetics Behavior Study

RecruitingHealthy volunteers welcome
  • Penn Medicine Center for Weight and Eating Disorders, Philadelphia
Ages 5 to 7 · All sexes · Updated Oct 30, 2025 · NCT05783765

Foundational Programs to Combat Clinician Stress

RecruitingHealthy volunteers welcome
  • Hospital of the University of Pennsylvania, Philadelphia
  • Penn Presbyterian Medical Center, Philadelphia
  • Pennsylvania Hospital, Philadelphia
Ages 25 to 70 · All sexes · Updated Oct 23, 2025 · NCT07220421

Army-SPRING Army-Suicide Prevention Research

RecruitingPhase 1Healthy volunteers welcome
  • Center for the Treatment and Study of Anxiety, University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Oct 20, 2025 · NCT06547008

A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data

RecruitingObservational studyHealthy volunteers welcome
  • Lankenau Medical Center, Paoli · 18 mi away
Ages 18 to 120 · All sexes · Updated Oct 20, 2025 · NCT06877884

Aimmune Longitudinal Collaboration Study

RecruitingHealthy volunteers welcome
  • Aimmune Therapeutics Manufacturing, Ambler · 14 mi away
  • GoodNature Tempe, Ambler · 14 mi away
Ages 18 to 50 · All sexes · Updated Oct 20, 2025 · NCT07218640

Neurophysiologic Biomarkers in Rett Syndrome

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 1 to 18 · Women · Updated Oct 20, 2025 · NCT05932589

PET Tau - Neurodegenerative Disease Imaging

RecruitingPhase 2/3Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 100 · All sexes · Updated Oct 15, 2025 · NCT03143374

Plantar Fasciitis Randomized Clinical Control Trial

RecruitingHealthy volunteers welcome
  • Penn Presbyterian Medical Center, Philadelphia
Ages 18 and older · All sexes · Updated Oct 10, 2025 · NCT03231150

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Oct 7, 2025 · NCT01193075

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated Oct 7, 2025 · NCT01193088

Philly CEAL- DECIDE+ Adaptation

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 35 to 75 · All sexes · Updated Oct 1, 2025 · NCT06732102

Studying Health Outcomes After Treatment in Patients With Retinoblastoma

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
All ages · All sexes · Updated Sep 19, 2025 · NCT03932786

Physiological Effects of ANGPTL3 Variants in Humans

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 10, 2025 · NCT04234724

InformationSeekingMesolimbicEngagementStudy2

RecruitingHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 to 45 · All sexes · Updated Sep 5, 2025 · NCT06257433

Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF)

RecruitingObservational studyHealthy volunteers welcome
  • Penn Dental Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Aug 27, 2025 · NCT06545084

Real-time fMRI for Insular Cortex Brain State-triggered Experience Sampling

RecruitingHealthy volunteers welcome
  • Drexel University, Philadelphia
Ages 18 to 35 · All sexes · Updated Aug 22, 2025 · NCT05855525

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 120 · All sexes · Updated Jul 25, 2025 · NCT05237258

Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University Hospitals, Philadelphia
Ages 18 and older · All sexes · Updated Jul 23, 2025 · NCT06632587

InSpace Accelerated Rehabilitation Study

RecruitingHealthy volunteers welcome
  • The Rothman Institute, Philadelphia
Ages 65 and older · All sexes · Updated May 29, 2025 · NCT05329584

Airway Data Collection With the Entarik Feeding Tube System

RecruitingHealthy volunteers welcome
  • Temple University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated May 13, 2025 · NCT06760572

Screen Smart: Using Digital Health to Improve HIV Screening and Prevention

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 15 to 21 · All sexes · Updated May 4, 2025 · NCT06003192

Temple Health Chest Initiative (THCI 2.0)

RecruitingObservational studyHealthy volunteers welcome
  • Temple University Of the Commonwealth System of Higher Education, Philadelphia
Ages 50 to 80 · All sexes · Updated Apr 18, 2025 · NCT06933758

Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines

RecruitingHealthy volunteers welcome
  • Monell Chemical Senses Center, Philadelphia
Ages 18 to 60 · All sexes · Updated Apr 16, 2025 · NCT06929455

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Apr 11, 2025 · NCT05564936

The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.

RecruitingHealthy volunteers welcome
  • Drexel University - Health Sciences Building, Philadelphia
Ages 18 to 40 · All sexes · Updated Nov 22, 2024 · NCT06274385

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · Women · Updated Nov 22, 2024 · NCT06419803

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · Women · Updated Nov 21, 2024 · NCT06419777

Reducing Urban Cervical Cancer Disparities

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Ages 18 to 90 · Women · Updated Oct 26, 2024 · NCT06416150

Novel Glaucoma Diagnostics

RecruitingObservational studyHealthy volunteers welcome
  • Wills Eye Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Aug 15, 2024 · NCT00286637

Genomic Risk in Retroperitoneal Sarcoma

RecruitingObservational studyHealthy volunteers welcome
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated May 31, 2024 · NCT06436846

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

RecruitingHealthy volunteers welcome
  • Center for Interventional Pain and Spine, Chadds Ford · 23 mi away
Ages 18 and older · All sexes · Updated Aug 18, 2022 · NCT05504499

Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging

RecruitingPhase 1/2Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jul 16, 2020 · NCT04275453

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.