Healthy volunteer studies in Rochester, MN
116 studies at sites in and around Rochester accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Development of a Noninvasive Metric to Measure Small Bowel Sensation - The Small Intestine Stress Test
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Obstructive Sleep Apnea Among Somali-Americans
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
GBPDC: Gut-Brain in PD Consortium Master Protocol
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Building and Gonda Building, Rochester
Lower Body Negative Pressure to Validate Physiological Monitors
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Effectiveness of an 8-week Independent Cadence Retraining Program on Stress Urinary Incontinence in Parous Runners.
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Study of Disrupted Sleep in Somali Americans
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A Novel Molecular Approach to Blood DNA Screening for Cancer: Specificity Assessment (The NOMAD Study)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Pain Control for Undergoing Costal Cartilage Harvesting
RecruitingPhase 4Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Observational, Non-Interventional Study Supporting Validation of eVO2peak Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Beetroot Juice and Sleep
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
RecruitingPhase 1/2Healthy volunteers welcome
- Mayo Clinic, Rochester
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
RecruitingPhase 4Healthy volunteers welcome
- Mayo Clinic, Rochester
Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Understanding Mechanisms of Normal and Disordered Defecation
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Sleep Restriction and Parental History of Hypertension
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Metabolic and Physiologic Responses to Hormone Therapy in Transgender and Gender Diverse People
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
The Effects of Sleep on Human Microbiota: Implications for Health and Disease
RecruitingHealthy volunteers welcome
- Mayo Clinic Rochester, Rochester
Fibrosis Lessens After Metabolic Surgery
RecruitingPhase 4Healthy volunteers welcome
- Mayo Clinic, Rochester
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic Rochester, Rochester
Tissue Destruction and Healing in Celiac Disease
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Prescription of Letrozole for Uterine Myoma
RecruitingPhase 4Healthy volunteers welcome
- Mayo Clinic, Rochester
A Study of TopSpin360 Training Device
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Comprehensive HHT Outcomes Registry of the United States (CHORUS)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Imaging Studies in Corticobasal Syndrome
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects
RecruitingPhase 4Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
BoxX-NoAF Clinical Trial
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Breastmilk in Response to a Bout of Exercise
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
RecruitingHealthy volunteers welcome
- Mayo Clinic Rochester, Rochester
Hot Flashes and Neurovascular Function in Women
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Deciphering Preserved Autonomic Function After Multiple Sclerosis
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation
RecruitingEarly phase 1Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Late Onset Alzheimer's Disease
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study of Invasive Hemodynamic for MACHD Registry
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic Rochester, Rochester
Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Adipose Tissue Blood Flow in Aging Humans
RecruitingHealthy volunteers welcome
- Mayo Clinic Minnesota, Rochester
Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Mayo AVC Registry and Biobank
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Circadian Rhythms in Human Adipose
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study of Niacin Regulation
RecruitingEarly phase 1Healthy volunteers welcome
- Mayo Clinic, Rochester
Regional Lipolysis Insulin Regulation
RecruitingEarly phase 1Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
A Global Study of the PETAL Consortium
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Multi-Cancer Detection Observational Cohort Study
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.
RecruitingPhase 4Healthy volunteers welcome
- Mayo Clinic, Rochester
Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma
RecruitingEarly phase 1Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Shear-wave Elastography Compared to Respiratory Function Testing
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A Prospective Registry for Patients at High-Risk for Pancreatic Cancer
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Gut Microbiome Studies in Patients With POEMS Syndrome and Other Plasma Cell Disorders
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Screening and Staging of Benign vs Malignant Pelvic Abnormalities
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Biobank for Cholestatic Liver Diseases.
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Implications of the Human Microbiota for Health and Disease
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Voices: Messages of Wisdom and Hope in the Face of Illness
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Insulin Regulation of Lipolysis and Lipolysis Proteins
RecruitingEarly phase 1Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma
RecruitingHealthy volunteers welcome
- Mayo Clinic Rochester, Rochester
The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Mechanisms of Anabolic Resistance in Older Humans
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study of SCAD Using Stress Contrast Echocardiography
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
The Role of Islet GLP-1 in the Pathogenesis of Prediabetes
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Understanding of Genetics by Men at Risk for Prostate Cancer
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
A Study of Mayo Clinic CV Research Heart & Voice Study
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:
RecruitingPhase 2Healthy volunteers welcome
- Mayo Clinic, Rochester
Family Study of Lymphoproliferative Disorders
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic, Rochester
Weight Loss Through Mayo Clinic Diet
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Insulin and Insulin Pulses During Fasting
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Accelerated Resolution Therapy for Early Maladaptive Grief
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Techquity by FAITH!
RecruitingHealthy volunteers welcome
- Mayo Clinic in Rochester, Rochester
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
InSpace Accelerated Rehabilitation Study
RecruitingHealthy volunteers welcome
- Mayo Clinic, Rochester
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
RecruitingPhase 3Healthy volunteers welcome
- Mayo Clinic, Rochester
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.