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Healthy volunteer studies in Boston, MA

303 studies at sites in and around Boston accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Patient-Centered Surgical Prehabilitation

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 to 85 · All sexes · Updated Sep 30, 2026 · NCT05715684

CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 60 and older · All sexes · Updated Sep 30, 2026 · NCT06133842

Following the Sound of Music

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 60 to 101 · All sexes · Updated Sep 30, 2026 · NCT07772765

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

RecruitingObservational studyHealthy volunteers welcome
  • Mass General Brigham, Boston
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT06517186

HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

RecruitingObservational studyHealthy volunteers welcome
  • Mass General Brigham, Boston
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634

Improving Spatial Perception and Speech Understanding in Multitalker Mixtures

RecruitingHealthy volunteers welcome
  • Boston University, Boston
Ages 18 to 80 · All sexes · Updated Sep 28, 2026 · NCT05260307

Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)

RecruitingHealthy volunteers welcome
  • Brigham & Women's Hospital, Boston
Ages 18 to 40 · Women · Updated Sep 28, 2026 · NCT04026893

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

GBPDC: Gut-Brain in PD Consortium Master Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

RecruitingPhase 3Healthy volunteers welcome
  • Boston Medical Center, Boston
1 Day – 49 Years · All sexes · Updated Sep 25, 2026 · NCT07160244

A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 64 · All sexes · Updated Sep 25, 2026 · NCT07536308

Dominantly Inherited Alzheimer Network (DIAN)

RecruitingObservational studyHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT00869817

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • Boston Clinical Trials- Site Number : 8400070, Boston
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

RecruitingPhase 3Healthy volunteers welcome
  • Boston Medical Center, Boston
Ages 0 and older · All sexes · Updated Sep 24, 2026 · NCT06866405

PrEP4U: Assessing the Effectiveness of Integrated Same-Day Lenacapavir Initiation and Follow-up Choice on PrEP Persistence

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital Sexual Health Clinic, Boston
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07335289

Nutrition for Precision Health, Powered by the All of Us

RecruitingHealthy volunteers welcome
  • Tufts University, Boston
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05701657

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06094257

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

RecruitingHealthy volunteers welcome
  • 111 Cummington Mall. Room 264, Boston
Ages 50 to 100 · All sexes · Updated Sep 23, 2026 · NCT06094192

Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
6 Months – 8 Years · All sexes · Updated Sep 22, 2026 · NCT04639830

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

RecruitingPhase 3Healthy volunteers welcome
  • New England College of Optometry, Boston
Ages 6 to 11 · All sexes · Updated Sep 21, 2026 · NCT07567040

A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 50 · All sexes · Updated Sep 21, 2026 · NCT07565090

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Boston Children s Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • and 1 more
1 Month – 100 Years · All sexes · Updated Sep 18, 2026 · NCT02450851

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS), Boston
Ages 18 to 60 · All sexes · Updated Sep 18, 2026 · NCT06665646

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Boston
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

Effect of Physical Activity Pattern on Cardiometabolic Health

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 45 · All sexes · Updated Sep 16, 2026 · NCT05838508

Safety and Tolerability Trial of Psilocybin in Healthy Older Adults

RecruitingPhase 1Healthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 65 to 85 · All sexes · Updated Sep 16, 2026 · NCT07516405

Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)

RecruitingPhase 4Healthy volunteers welcome
  • Joslin Diabetes Center, Boston
Ages 18 to 70 · All sexes · Updated Sep 14, 2026 · NCT07818707

Medical Residents Learning Weight Management Counseling Skills

RecruitingHealthy volunteers welcome
  • Boston University, Boston
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06529666

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Boston Childrens Hospital, Boston
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

THE GUIDE: Transforming Health for Young Adults Using Interventions to Drive Engagement

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 18 to 29 · All sexes · Updated Sep 9, 2026 · NCT06177600

Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 30 to 40 · Women · Updated Sep 8, 2026 · NCT06866119

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • VA Boston Healthcare System, Boston
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

RecruitingObservational studyHealthy volunteers welcome
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 30 to 90 · All sexes · Updated Sep 1, 2026 · NCT04124029

Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)

RecruitingPhase 1/2Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07601425

Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program

RecruitingHealthy volunteers welcome
  • METCO, Boston
  • Boston University, Boston
Ages 14 and older · All sexes · Updated Sep 1, 2026 · NCT06736522

A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS) (Site ID: 30007), Boston
Ages 18 to 55 · All sexes · Updated Sep 1, 2026 · NCT07390955

Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT03480633

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Brigham, Boston
Ages 20 to 79 · All sexes · Updated Aug 25, 2026 · NCT07780890

Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 12 to 55 · All sexes · Updated Aug 25, 2026 · NCT07287033

Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Mass General Brigham Cancer Institute at Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07139769

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Brigham, Boston
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Brigham, Boston
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

EpiFaith Resident Learning Curve Trial

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07395622

Registry of Asthma Characterization and Recruitment 3 (RACR3)

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital: Department of Immunology, Boston
All ages · All sexes · Updated Aug 21, 2026 · NCT05272241

Ultrasound Therapy In Cardiac Amyloidosis

RecruitingPhase 4Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 90 · All sexes · Updated Aug 21, 2026 · NCT04667494

OCT Vibrography for Biomechanical Properties of Tissues

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 75 · All sexes · Updated Aug 19, 2026 · NCT05759780

Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Aug 19, 2026 · NCT07772167

Groceries for Residents of Southeastern USA to Stop Hypertension

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06891911

Experiment 3: Mixed vs Blocked; Dashboard Paradigm

RecruitingHealthy volunteers welcome
  • Brigham & Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06934213

Mixed Vs Blocked Search: Four Unique Tasks

RecruitingHealthy volunteers welcome
  • Brigham & Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06933693

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Local Institution - 0024, Boston
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Dana Farber Cancer Institute, Boston
All ages · All sexes · Updated Aug 17, 2026 · NCT05463796

Artificial Intelligence-Based Health Assessment From Face Photographs - Healthy Volunteer Study

RecruitingObservational studyHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07719049

Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy

RecruitingPhase 2Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 65 · Women · Updated Aug 13, 2026 · NCT06483659

Brain Stimulation Paired With Structured Language Learning in Adults

RecruitingHealthy volunteers welcome
  • General Neuro, Inc., Boston
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07762118

Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease

RecruitingHealthy volunteers welcome
  • Boston University Neuromotor Recovery Laboratory, Boston
Ages 50 to 90 · All sexes · Updated Aug 13, 2026 · NCT07659964

Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota

RecruitingHealthy volunteers welcome
  • Lindus Health, Boston
Ages 20 to 40 · All sexes · Updated Aug 7, 2026 · NCT07243574

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

RecruitingPhase 1Healthy volunteers welcome
  • Boston Medical Center, Boston
  • Massachusetts General Hospital (MGH), Charlestown · 1 mi away
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07258836

Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

RecruitingPhase 1Healthy volunteers welcome
  • Beth Israel Deaconess Medical Center VCRS (BIDMC VCRS Site # 32077), Boston
Ages 18 to 55 · All sexes · Updated Aug 6, 2026 · NCT07390474

Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias

RecruitingObservational studyHealthy volunteers welcome
  • Harvard University, Boston
Ages 6 and older · All sexes · Updated Aug 3, 2026 · NCT01060371

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 45 to 74 · Women · Updated Jul 31, 2026 · NCT05625659

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

RecruitingHealthy volunteers welcome
  • Center for Anxiety and Related Disorders, Boston
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT05567640

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07020533

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Boston University, Boston
  • Massachusetts General Hospital, Boston
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety

RecruitingHealthy volunteers welcome
  • Center for Anxiety and Related Disorders at Boston University, Boston
Ages 18 to 50 · All sexes · Updated Jul 23, 2026 · NCT05683223

Diffuse Cutaneous Scleroderma (DSSc) SFDI Study

RecruitingHealthy volunteers welcome
  • Shapiro Outpatient Rheumatology Clinic at Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07090226

Neuromodulation for a Novel OCD Biomarker and Treatment

RecruitingHealthy volunteers welcome
  • Boston University Center for Anxiety and Related Disorders (BU-CARD), Boston
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT05994053

The Osteoarthritis Prevention Study

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 50 and older · Women · Updated Jul 23, 2026 · NCT05946044

Memory Enhancement in Aging With Optimal Dosing

RecruitingHealthy volunteers welcome
  • 111 Cummington Mall, Boston
Ages 65 and older · All sexes · Updated Jul 22, 2026 · NCT07461584

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

RecruitingPhase 1/2Healthy volunteers welcome
  • Tufts Medical Center, Boston
Ages 18 to 100 · All sexes · Updated Jul 21, 2026 · NCT06649110

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

RecruitingHealthy volunteers welcome
  • Boston University Charles River Campus, Boston
  • Boston University, Boston
Ages 18 to 50 · All sexes · Updated Jul 21, 2026 · NCT07459803

Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 15 to 18 · All sexes · Updated Jul 21, 2026 · NCT07173608

Alcohol and "Heat of the Moment" Sexual Decision Making

RecruitingHealthy volunteers welcome
  • Boston University Department of Psychological and Brain Sciences, Boston
Ages 18 and older · Men · Updated Jul 20, 2026 · NCT05729256

Neural Mechanisms of Family-Focused Treatment for Youth Depression

RecruitingHealthy volunteers welcome
  • Boston University, Boston
  • Athinoula A. Martinos Imaging Center at Massachusetts Institute of Technology, Charlestown · 1 mi away
Ages 7 to 12 · All sexes · Updated Jul 20, 2026 · NCT06289010

Defibrotide for the Treatment of Severe COVID-19

RecruitingPhase 2Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 100 · All sexes · Updated Jul 20, 2026 · NCT04652115

Non-Invasive Preeclampsia Screening and Biobank

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · Women · Updated Jul 20, 2026 · NCT06643741

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Jul 17, 2026 · NCT06259292

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

RecruitingHealthy volunteers welcome
  • Boston University, Boston
Ages 15 and older · Women · Updated Jul 17, 2026 · NCT05624931

Restructuring the Alpha-Gamma Code in Aging Vision

RecruitingEarly phase 1Healthy volunteers welcome
  • 111 Cummington Mall, Boston University, Boston
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT07208318

Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 60 and older · Women · Updated Jul 16, 2026 · NCT02290834

Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Charlestown · 1 mi away
Ages 18 to 55 · All sexes · Updated Jul 16, 2026 · NCT04940663

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)

RecruitingHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06469307

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
  • Massachusetts General Hospital, Boston
Ages 40 to 80 · All sexes · Updated Jul 15, 2026 · NCT06716580

Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Charlestown · 1 mi away
Ages 50 to 80 · All sexes · Updated Jul 14, 2026 · NCT05904132

Resilient Families Feasibility Trial

RecruitingHealthy volunteers welcome
  • Mass General Brigham, Boston
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07383948

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 22 and older · All sexes · Updated Jul 14, 2026 · NCT05361941

ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL

RecruitingPhase 4Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
All ages · Women · Updated Jul 13, 2026 · NCT06146842

Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients

RecruitingObservational studyHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
All ages · Women · Updated Jul 13, 2026 · NCT02193542

Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Jul 13, 2026 · NCT05829044

ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia

RecruitingPhase 4Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 50 · Women · Updated Jul 13, 2026 · NCT05543694

A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

RecruitingHealthy volunteers welcome
  • Brigham & Women's Hospital, Boston
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Jul 9, 2026 · NCT03882073

Care Transitions App for Patients With Multiple Chronic Conditions

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 55 and older · All sexes · Updated Jul 9, 2026 · NCT06051058

AMI Construction in Lower Extremity Residual Limbs

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 65 · All sexes · Updated Jul 9, 2026 · NCT04063592

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

RecruitingPhase 4Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Jul 8, 2026 · NCT06003153

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT00682695

Protocol CAUSE-03 / CHEETAH

RecruitingObservational studyHealthy volunteers welcome
  • Boston University School of Medicine: Pulmonary Center, Boston
  • Boston Children's Hospital: Department of Immunology, Boston
Ages 6 to 17 · All sexes · Updated Jul 1, 2026 · NCT06136091

Cervical Preparation for Same-Day Dilation & Evacuation

RecruitingHealthy volunteers welcome
  • Boston Medical Center, Boston
Ages 16 and older · Women · Updated Jun 30, 2026 · NCT06799052

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

The Actuate-CBC Study

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital Sumner Redstone Burn Center, Boston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05917652

Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care

RecruitingHealthy volunteers welcome
  • Fenway Community Health, Boston
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT05241990

A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute (Data Collection Only), Boston
Ages 45 and older · Women · Updated Jun 24, 2026 · NCT06312124

Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait

RecruitingHealthy volunteers welcome
  • Massachusetts Eye and Ear, Harvard Medical School, Boston
Ages 21 and older · All sexes · Updated Jun 23, 2026 · NCT06688578

Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT05671133

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 0 to 21 · All sexes · Updated Jun 22, 2026 · NCT05071144

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 55 to 90 · All sexes · Updated Jun 18, 2026 · NCT05776641

Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism

RecruitingHealthy volunteers welcome
  • Dauten Family Center for Bipolar Treatment Innovation, Boston
Ages 18 to 65 · All sexes · Updated Jun 17, 2026 · NCT07649161

Childhood Cancer Survivor Study

RecruitingObservational studyHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Jun 12, 2026 · NCT05796908

Assessing MB-Spirit for Psychological Well-being

RecruitingHealthy volunteers welcome
  • 149 13th St, Boston
  • Charlestown Navy Yard Campus, Boston
Ages 18 to 50 · All sexes · Updated Jun 11, 2026 · NCT07325448

Hereditary Risk Factors for Thyroid Cancer

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute, Boston
All ages · All sexes · Updated Jun 11, 2026 · NCT02747888

Wearable Evaluation of Ambulatory Readings for Blood Pressure

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 100 · All sexes · Updated Jun 11, 2026 · NCT06610448

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

RecruitingHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · Women · Updated Jun 10, 2026 · NCT07220239

Project EMPOWER-OCD

RecruitingHealthy volunteers welcome
  • Boston University, Boston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07158801

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

RecruitingObservational studyHealthy volunteers welcome
  • Brigham & Women's Hospital, Boston
  • Boston Medical Center, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 15 to 55 · Women · Updated Jun 4, 2026 · NCT06030063

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

RecruitingObservational studyHealthy volunteers welcome
  • Tufts Medical Center, Boston
  • Boston Medical Center, Boston
Ages 50 and older · All sexes · Updated Jun 4, 2026 · NCT06034405

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 30 to 65 · All sexes · Updated Jun 3, 2026 · NCT04496947

Multisite Implementation of COMPRENDO

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute/Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06055296

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

RecruitingEarly phase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 29, 2026 · NCT06122896

Category Learning Retention in Adults With and Without Developmental Language Disorder

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 55 · All sexes · Updated May 29, 2026 · NCT05901493

Effectiveness of Cognitive Training in Older and Younger Adults

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 85 · All sexes · Updated May 29, 2026 · NCT06375681

Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated May 29, 2026 · NCT07614906

A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 45 · Women · Updated May 26, 2026 · NCT07312227

Impulsivity Domains and Subjective Response

RecruitingEarly phase 1Healthy volunteers welcome
  • Northeastern University, Boston
Ages 21 to 25 · All sexes · Updated May 22, 2026 · NCT05929677

Ph 2 Elacestrant in ER Positive Uterine Sarcomas

RecruitingPhase 2Healthy volunteers welcome
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · Women · Updated May 22, 2026 · NCT07467772

Word Learning in Bilingual Typical and Late Talking Children: The Role of Meaning and Input

RecruitingHealthy volunteers welcome
  • Boston University, Boston
24 Months – 30 Months · All sexes · Updated May 20, 2026 · NCT07600242

Multi-Component Breath Alcohol Intervention Phase 3

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 25 · All sexes · Updated May 20, 2026 · NCT06994962

mTBI Identification and Monitoring Through Retinal Scanning

RecruitingObservational studyHealthy volunteers welcome
  • Boston Medical Center Concussion Clinic, Ryan Center for Sports Medicine & Rehabilitation at Boston University, Boston
Ages 18 to 45 · All sexes · Updated May 20, 2026 · NCT06142435

Effect of Mindfulness-based Neurofeedback for Adolescents With Elevated Repetitive Negative Thinking

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Center for Addiction Medicine, 101 Merrimac Street, Suite 320, Boston, MA 02114, Boston
Ages 13 to 21 · All sexes · Updated May 19, 2026 · NCT07055217

Overcoming the Barriers to Effective Transcranial Temporal Interference Stimulation in Humans

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 65 · All sexes · Updated May 18, 2026 · NCT07593859

Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06989593

Testing Effects of Melatonin on Uterine Contractions in Women

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 35 · Women · Updated May 18, 2026 · NCT05358834

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

RecruitingEarly phase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 40 to 99 · All sexes · Updated May 6, 2026 · NCT06538311

Music Use in Parturients Admitted to Labor & Delivery

RecruitingHealthy volunteers welcome
  • Tufts Medical Center, Boston
Ages 18 and older · Women · Updated May 1, 2026 · NCT06969105

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

RecruitingHealthy volunteers welcome
  • President and Fellows of Harvard College, T.H. Chan School, Boston
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06251323

Effects of Age, Sex and Isometric Exercise on Ventricular-Vascular Interactions During Cardiac Unloading

RecruitingHealthy volunteers welcome
  • University of Massachusetts Boston, Boston
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT06939153

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

RecruitingPhase 3Healthy volunteers welcome
  • Lindus Health (Virtual Study Site), Boston
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT07280065

A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser

RecruitingHealthy volunteers welcome
  • MGH Clinical Unit for Research Trials & Outcomes in Skin, Boston
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06295471

Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 13 to 17 · All sexes · Updated Apr 24, 2026 · NCT03741777

Cognitive Function and Affective Regulation in Meditators

RecruitingObservational studyHealthy volunteers welcome
  • BIDMC, Boston
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07546786

PET/MRI/EEG Imaging Study in Epilepsy

RecruitingObservational studyHealthy volunteers welcome
  • Athinoula A. Martinos Center, Charlestown · 1 mi away
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06974305

Individualizing Approaches to Surveillance Mammography in Older Breast Cancer Survivors - The I-MAMMO Study

RecruitingPhase 2Healthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 80 and older · Women · Updated Apr 22, 2026 · NCT07123649

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

RecruitingPhase 3Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Boston Children's Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT03295981

Mediators and Moderators of Auditory Training

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 85 · All sexes · Updated Apr 20, 2026 · NCT06812273

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

RecruitingPhase 4Healthy volunteers welcome
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT04419272

Combined Anabolic Therapy

RecruitingPhase 4Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 45 and older · Women · Updated Apr 17, 2026 · NCT06558188

Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder

RecruitingHealthy volunteers welcome
  • Martinos Center for Biomedical Research, Building 149, 13th Street, Charlestown · 1 mi away
Ages 18 to 45 · All sexes · Updated Apr 15, 2026 · NCT06373016

Biomarkers in Infection

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Apr 15, 2026 · NCT02545478

The Effect of Sleep Loss on Emotion Regulation

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 40 · All sexes · Updated Apr 14, 2026 · NCT05393830

Dance and Energy Expenditure Among Adults With Parkinson's

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 85 · All sexes · Updated Apr 13, 2026 · NCT06425731

Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 5 and older · All sexes · Updated Apr 9, 2026 · NCT06839469

A Global Study of the PETAL Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06067347

An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT07421830

Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General, Boston
Ages 18 to 85 · All sexes · Updated Apr 3, 2026 · NCT04661215

Muscle Health Measurements Using Electrical Impedance Myography

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 89 · All sexes · Updated Apr 3, 2026 · NCT07502989

Gastric Assessment of Pediatric Patients Undergoing Surgery

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 2 to 18 · All sexes · Updated Apr 2, 2026 · NCT05674643

Neonatal Platelet Transfusion Threshold Trial

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
1 Hour – 48 Hours · All sexes · Updated Mar 25, 2026 · NCT06676904

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
All ages · All sexes · Updated Mar 24, 2026 · NCT05407129

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Up to age 30 · All sexes · Updated Mar 18, 2026 · NCT04712812

NIRS Monitoring in Premature Infants

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
0 Months – 12 Months · All sexes · Updated Mar 18, 2026 · NCT02601339

Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated Mar 16, 2026 · NCT06618040

ACT Lung Health Intervention: Phase Two

RecruitingHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
  • University of Massachusetts-Boston, Boston
Ages 18 to 100 · All sexes · Updated Mar 13, 2026 · NCT06945120

Preventing Depression of Chinese American Adolescents by RRE

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 14 to 18 · All sexes · Updated Mar 13, 2026 · NCT05921201

Postnatal Exercise to Activate Baby's Brown Fat

RecruitingHealthy volunteers welcome
  • Joslin Diabetes Center, Boston
Ages 18 to 45 · Women · Updated Mar 12, 2026 · NCT07467694

Mapping and Quantifying Lymphatic Drainage of the Arm's Alternate Pathway

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · Women · Updated Mar 11, 2026 · NCT05253352

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

RecruitingPhase 2Healthy volunteers welcome
  • DFCI/BWH Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Mar 10, 2026 · NCT06059391

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

RecruitingPhase 4Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 8 to 18 · All sexes · Updated Mar 6, 2026 · NCT06853665

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 100 · All sexes · Updated Mar 6, 2026 · NCT05881239

A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans

RecruitingHealthy volunteers welcome
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 to 65 · All sexes · Updated Mar 6, 2026 · NCT05995678

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital (MGH) / Harvard, Boston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06196008

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

RecruitingHealthy volunteers welcome
  • Brigham and Womens Hospital, Boston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06252129

Hematoma Block for Distal Radius Fracture

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 100 · All sexes · Updated Mar 3, 2026 · NCT02346929

Positron Emission Tomography (PET) Imaging of Thrombosis

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Feb 27, 2026 · NCT03830320

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study

RecruitingHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 45 and older · All sexes · Updated Feb 27, 2026 · NCT06523868

Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT

RecruitingHealthy volunteers welcome
  • Harvard Dental Center, Boston
Ages 20 to 80 · All sexes · Updated Feb 27, 2026 · NCT07440303

Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 80 · All sexes · Updated Feb 27, 2026 · NCT03535545

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute, Boston
Ages 18 to 45 · All sexes · Updated Feb 24, 2026 · NCT05740839

Lung Cancer Screening in High-risk Black Individuals

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital Cancer Center, Boston
Ages 50 to 80 · All sexes · Updated Feb 23, 2026 · NCT05898594

TMS for Cognitive Decline in Aging and Preclinical AD

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 40 to 99 · All sexes · Updated Feb 20, 2026 · NCT06956300

Effects of Neuromodulation in Laryngeal Dystonia

RecruitingHealthy volunteers welcome
  • Teresa J Kimberley, Boston
Ages 21 to 85 · All sexes · Updated Feb 20, 2026 · NCT05095740

Phase 1a Single Ascending Dose Study of MIB-725 in Healthy Adults

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 19 to 60 · All sexes · Updated Feb 19, 2026 · NCT06815991

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
1 Day · All sexes · Updated Feb 11, 2026 · NCT03059420

Intermuscular Coherence as a Biomarker for ALS

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 20 to 90 · All sexes · Updated Feb 9, 2026 · NCT05104710

Modulation of Brain Oscillations Underlying Working Memory

RecruitingHealthy volunteers welcome
  • Martinos Center for Biomedical Imaging, Charlestown · 1 mi away
Ages 18 to 35 · All sexes · Updated Feb 9, 2026 · NCT05923606

Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy

RecruitingPhase 4Healthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 21 to 85 · Men · Updated Feb 6, 2026 · NCT05895383

The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response

RecruitingEarly phase 1Healthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
  • Boston University, Boston
Ages 18 to 45 · All sexes · Updated Feb 5, 2026 · NCT06983730

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Feb 4, 2026 · NCT01694940

Linked Outcomes in Various EEG-Hyperscanning Setups

RecruitingObservational studyHealthy volunteers welcome
  • Spaulding Rehabilitation Hospital, Charlestown · 1 mi away
Ages 20 to 60 · All sexes · Updated Feb 3, 2026 · NCT07385027

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Feb 2, 2026 · NCT04005976

Molecular Imaging of NET Using [C-11]MRB-PET in MS

RecruitingPhase 1/2Healthy volunteers welcome
  • Brigham MS Center, 60 Fenwood Road, Boston
Ages 18 to 60 · All sexes · Updated Feb 2, 2026 · NCT03207464

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 14 and older · All sexes · Updated Jan 30, 2026 · NCT05332639

PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

RecruitingPhase 1/2Healthy volunteers welcome
  • Brigham MS Center, 60 Fenwood Road, Boston
Ages 18 to 85 · All sexes · Updated Jan 28, 2026 · NCT02649985

REcovery From DEXmedetomidine-induced Unconsciousness

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Jan 22, 2026 · NCT06003127

Maternal Newborn Health Registry

RecruitingObservational studyHealthy volunteers welcome
  • Boston University, Boston
All ages · All sexes · Updated Jan 21, 2026 · NCT01073475

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study

RecruitingHealthy volunteers welcome
  • Dana-Farber Cancer Institute, Boston
Ages 22 and older · All sexes · Updated Jan 20, 2026 · NCT06450171

The CurePSP Genetics Program

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 35 and older · All sexes · Updated Jan 14, 2026 · NCT06647641

The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)

RecruitingHealthy volunteers welcome
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 55 to 69 · Men · Updated Jan 13, 2026 · NCT05926102

Glucose Consumption in MS Using [F-18]FDG-PET

RecruitingPhase 4Healthy volunteers welcome
  • Brigham & Women's Hospital, Boston
Ages 18 to 70 · All sexes · Updated Jan 9, 2026 · NCT07087106

Assessment of Synaptic Density in MS

RecruitingEarly phase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 60 · All sexes · Updated Jan 9, 2026 · NCT04634994

Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

RecruitingHealthy volunteers welcome
  • New Balance Foundation Obesity Prevention Center, Boston
Ages 9 to 12 · All sexes · Updated Jan 8, 2026 · NCT05464186

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

RecruitingHealthy volunteers welcome
  • New England College of Optometry, Boston
Ages 6 to 8 · All sexes · Updated Dec 29, 2025 · NCT06034327

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 12 to 25 · All sexes · Updated Dec 29, 2025 · NCT06038318

Diffusion MRI in Heart Failure

RecruitingEarly phase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Charlestown · 1 mi away
Ages 18 to 85 · All sexes · Updated Dec 24, 2025 · NCT02973633

PET Imaging Evaluation of [11C]SY08

RecruitingEarly phase 1Healthy volunteers welcome
  • MGH, Charlestown · 1 mi away
Ages 50 to 80 · All sexes · Updated Dec 24, 2025 · NCT06098612

Executive Function Training for Children and Adolescents

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 12 to 17 · All sexes · Updated Dec 23, 2025 · NCT07147894

Imaging Histone Deacetylase in the Heart

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Dec 22, 2025 · NCT03549559

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

RecruitingPhase 1/2Healthy volunteers welcome
  • Boston Children's Hospital (Part C only), Boston
  • Brigham and Women's Hospital (Part C and Part D), Boston
Ages 12 to 65 · All sexes · Updated Dec 22, 2025 · NCT06239116

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 8 to 35 · All sexes · Updated Dec 19, 2025 · NCT04439552

A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 75 · All sexes · Updated Dec 16, 2025 · NCT07219537

Moderators and Mediators of Perceptual Learning

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 85 · All sexes · Updated Dec 15, 2025 · NCT05894967

Training Inner Speech in Children With Developmental Language Disorder

RecruitingHealthy volunteers welcome
  • MGH Institute of Health Professions, Boston
Ages 8 to 10 · All sexes · Updated Dec 15, 2025 · NCT06880731

MRI Assessment of Placental Health

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 18 to 45 · Women · Updated Dec 12, 2025 · NCT02297724

Developing Fast Pediatric Imaging

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Boston Children Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 0 and older · All sexes · Updated Dec 12, 2025 · NCT03761121

School Inner City Air Study

RecruitingHealthy volunteers welcome
  • Mass General Brigham, Boston
Ages 6 to 90 · All sexes · Updated Dec 11, 2025 · NCT05953233

Cognitive Control to Boost Physical Activity Adherence

RecruitingHealthy volunteers welcome
  • Center for Cognitive and Brain Health, Boston
Ages 40 to 65 · All sexes · Updated Dec 11, 2025 · NCT06338774

Advanced Fetal Imaging - Phase II

RecruitingHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 18 to 45 · Women · Updated Dec 8, 2025 · NCT02840019

Brain Networks in Dystonia

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts Eye and Ear, Boston
Ages 21 to 80 · All sexes · Updated Dec 8, 2025 · NCT03042962

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 65 · All sexes · Updated Dec 5, 2025 · NCT06105164

Dietary Intervention to Mitigate Adverse Consequences of Night Work

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 45 · All sexes · Updated Dec 5, 2025 · NCT04868526

Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts Eye and Ear and University of Utah, Boston
Ages 18 to 80 · All sexes · Updated Dec 2, 2025 · NCT05150106

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

RecruitingHealthy volunteers welcome
  • Massachusetts Eye and Ear Infirmary, Boston
All ages · All sexes · Updated Dec 2, 2025 · NCT05317390

Brain-Computer Interfaces in Laryngeal Dystonia

RecruitingHealthy volunteers welcome
  • Massachusetts Eye and Ear Infirmary, Boston
Ages 18 to 80 · All sexes · Updated Dec 2, 2025 · NCT04421365

Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor

RecruitingEarly phase 1Healthy volunteers welcome
  • Massachusetts Eye and Ear and University of California San Francisco, Boston
Ages 18 to 80 · All sexes · Updated Dec 2, 2025 · NCT05216770

An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus

RecruitingEarly phase 1Healthy volunteers welcome
  • Massachusetts Eye and Ear Infirmary, Boston
Ages 18 and older · All sexes · Updated Dec 2, 2025 · NCT04192773

CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood

RecruitingHealthy volunteers welcome
  • Boston Medical Center, Boston
3 Months · All sexes · Updated Dec 1, 2025 · NCT03641092

External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia

RecruitingObservational studyHealthy volunteers welcome
  • Joslin Diabetes Center, Boston
Ages 18 to 70 · All sexes · Updated Nov 28, 2025 · NCT07082478

A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients

RecruitingPhase 4Healthy volunteers welcome
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Nov 26, 2025 · NCT06934239

Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces

RecruitingHealthy volunteers welcome
  • Mass Eye and Ear, Boston
3 Months · All sexes · Updated Nov 26, 2025 · NCT05867173

Biomarker Development for Muscular Dystrophies

RecruitingObservational studyHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
  • Massachusetts General Hospital, Boston
Ages 5 and older · All sexes · Updated Nov 24, 2025 · NCT05019625

Extracellular RNA Biomarkers of Myotonic Dystrophy

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 5 and older · All sexes · Updated Nov 24, 2025 · NCT05020002

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665

Decompression Versus Decompression and Fusion

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT04542720

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute, Boston
Ages 18 to 59 · Women · Updated Nov 21, 2025 · NCT06322888

Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study

RecruitingHealthy volunteers welcome
  • Codman Square Health Center, Boston
  • East Boston Neighborhood Health Center, East Boston · 2 mi away
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT05524428

CRC Screening in Unscreened Individuals 45-54

RecruitingObservational studyHealthy volunteers welcome
  • Codman Square Health Center, Boston
Ages 45 to 54 · All sexes · Updated Nov 13, 2025 · NCT06757192

Positive Fit to Colonoscopy: Closing the Gap

RecruitingObservational studyHealthy volunteers welcome
  • Codman Square Health Center, Boston
Ages 45 to 75 · All sexes · Updated Nov 13, 2025 · NCT06763432

Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
Ages 40 to 69 · Men · Updated Nov 10, 2025 · NCT06398639

Physiology of Human Brain Connectivity

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 64 · All sexes · Updated Nov 10, 2025 · NCT06246942

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 20 to 75 · All sexes · Updated Nov 6, 2025 · NCT02118922

Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.

RecruitingPhase 2Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 55 · All sexes · Updated Nov 5, 2025 · NCT07079761

The Physiology of Human Brown Adipose Tissue

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 75 · All sexes · Updated Oct 31, 2025 · NCT04352244

Assess Fibrin in Brains With AD/ADRD

RecruitingPhase 1/2Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 55 to 90 · All sexes · Updated Oct 30, 2025 · NCT05336695

Gut Mini-Pill Study

RecruitingHealthy volunteers welcome
  • Jean Mayer Human Nutrition Research Center on Aging, Boston
Ages 50 to 75 · All sexes · Updated Oct 30, 2025 · NCT07220369

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 13 to 20 · All sexes · Updated Oct 30, 2025 · NCT06216704

Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 13 to 20 · All sexes · Updated Oct 30, 2025 · NCT04508088

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

RecruitingPhase 1/2Healthy volunteers welcome
  • Mass Eye and Ear, Boston
Ages 18 and older · All sexes · Updated Oct 28, 2025 · NCT06033703

Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment

RecruitingPhase 4Healthy volunteers welcome
  • MGH, Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Oct 27, 2025 · NCT02283996

Mapping Auricular Vagus Nerve Circuitry

RecruitingEarly phase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Oct 24, 2025 · NCT00200889

National Pregnancy Registry for Psychiatric Medications

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 45 · Women · Updated Oct 24, 2025 · NCT01246765

Developing and Testing a Trauma-Informed Exercise Intervention for Women Veterans With Histories of Sexual Violence

RecruitingHealthy volunteers welcome
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 21 to 65 · Women · Updated Oct 23, 2025 · NCT06746740

Foundational Programs to Combat Clinician Stress

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 25 to 70 · All sexes · Updated Oct 23, 2025 · NCT07220421

Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System

RecruitingHealthy volunteers welcome
  • Massachusetts General hospital, Boston
Ages 14 to 85 · All sexes · Updated Oct 22, 2025 · NCT02947971

Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
All ages · All sexes · Updated Oct 22, 2025 · NCT07217561

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 75 · All sexes · Updated Oct 22, 2025 · NCT07033208

US Benchmarking Clinical Study

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Boston Medical Center, Boston
Ages 60 and older · All sexes · Updated Oct 20, 2025 · NCT07215715

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

RecruitingObservational studyHealthy volunteers welcome
  • Harvard/Massachusetts General Hospital, Boston
All ages · All sexes · Updated Oct 7, 2025 · NCT01193075

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

RecruitingObservational studyHealthy volunteers welcome
  • Harvard/Massachusetts General Hospital, Boston
All ages · All sexes · Updated Oct 7, 2025 · NCT01193088

ECA-enhanced Document Explanation RCT

RecruitingHealthy volunteers welcome
  • Tufts Medical Center, Boston
  • Northeastern University, Boston
Ages 18 and older · All sexes · Updated Oct 3, 2025 · NCT06435819

Targeting Specific Brain Networks to Treat Specific Symptoms in Depression

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Sep 29, 2025 · NCT05523817

Eating to Adjust the Timing System

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 45 · All sexes · Updated Sep 29, 2025 · NCT05800990

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS), Boston
Ages 18 to 55 · All sexes · Updated Sep 25, 2025 · NCT06796686

Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 50 · All sexes · Updated Sep 25, 2025 · NCT00595491

Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 50 and older · All sexes · Updated Sep 22, 2025 · NCT06001814

Vertical Soft Tissue Augmentation With CTG vs ADM

RecruitingHealthy volunteers welcome
  • Harvard School of Dental Medicine, Boston
Ages 18 to 99 · All sexes · Updated Sep 18, 2025 · NCT05729607

The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults

RecruitingHealthy volunteers welcome
  • Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston
Ages 65 and older · All sexes · Updated Sep 16, 2025 · NCT06940037

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Sep 10, 2025 · NCT04296604

Exercise, Brain Activity, and Weight Maintenance

RecruitingHealthy volunteers welcome
  • Joslin Diabetes Center, Boston
Ages 18 to 70 · All sexes · Updated Sep 4, 2025 · NCT06511310

Can Food Timing Reduce Your Diabetes Risk?

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 45 · All sexes · Updated Aug 6, 2025 · NCT05862818

Caries Detection With Two Different Caries Detecting Devices

RecruitingHealthy volunteers welcome
  • Tufts University School of Dental Medicine, Boston
Ages 21 and older · All sexes · Updated Aug 5, 2025 · NCT06152081

Medical Illustration Design Characteristic Evaluation

RecruitingHealthy volunteers welcome
  • Tufts Medical Center, Boston
  • Northeastern University, Boston
Ages 18 and older · All sexes · Updated Aug 3, 2025 · NCT06435806

Apple Health Study

RecruitingObservational studyHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 29, 2025 · NCT06958523

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 to 120 · All sexes · Updated Jul 25, 2025 · NCT05237258

Validating Gulf War Illness Blood Biomarkers

RecruitingObservational studyHealthy volunteers welcome
  • Boston University, Boston
Ages 35 and older · All sexes · Updated Jul 24, 2025 · NCT05736146

Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection

RecruitingObservational studyHealthy volunteers welcome
  • Tufts Medical Center, Boston
Ages 18 to 99 · All sexes · Updated Jul 20, 2025 · NCT05866952

Multimodal Musical Stimulation for Healthy Neurocognitive Aging

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 95 · All sexes · Updated Jul 10, 2025 · NCT06229093

TrialNet Pathway to Prevention of T1D

RecruitingObservational studyHealthy volunteers welcome
  • Joslin Diabetes Center, Boston
Ages 2 to 45 · All sexes · Updated Jul 1, 2025 · NCT00097292

Get Social Media and Risk-Reduction Training

RecruitingHealthy volunteers welcome
  • Boston University, Boston
All ages · Women · Updated Jun 11, 2025 · NCT06618586

TENS Unit for Analgesia During IUD Insertion

RecruitingHealthy volunteers welcome
  • Tufts Medical Center, Boston
Ages 12 to 50 · Women · Updated Jun 4, 2025 · NCT06240260

Communicating Uncertainties Associated With the Benefits and Risks of New Cancer Drugs

RecruitingHealthy volunteers welcome
  • Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston
Ages 18 and older · All sexes · Updated May 30, 2025 · NCT06997185

Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

RecruitingHealthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 55 and older · All sexes · Updated May 25, 2025 · NCT06989619

A Mobile Gaming App to Improve Adherence to PrEP

RecruitingHealthy volunteers welcome
  • Boston Medical Center, Boston
Ages 15 to 34 · All sexes · Updated May 14, 2025 · NCT05762705

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Charlestown · 1 mi away
Ages 18 to 45 · All sexes · Updated May 14, 2025 · NCT06386588

Tracing the Metabolic Flux of Orally Administered NAD+ Precursors

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated May 6, 2025 · NCT06882096

Behavioral Economics to Implement a Traffic Light Nutrition Ranking System: Study 2

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 90 · All sexes · Updated Apr 30, 2025 · NCT06298253

Exploratory Clinical Study to Assess Safety and Efficacy of Xenon Gas Inhalation to Control Neuroinflammation

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 55 to 75 · All sexes · Updated Apr 25, 2025 · NCT06945614

Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes

RecruitingHealthy volunteers welcome
  • T1D Exchange, Boston
  • T1D Exchange, Boston
Ages 2 to 95 · All sexes · Updated Apr 17, 2025 · NCT06931275

Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Feb 27, 2025 · NCT04699747

Mindfulness for Cognition in Early-stage Alzheimer's Disease

RecruitingHealthy volunteers welcome
  • VA Boston Healthcare System - Jamaica Plain Campus, Boston
Ages 50 to 100 · All sexes · Updated Jan 27, 2025 · NCT06792877

Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI

RecruitingPhase 4Healthy volunteers welcome
  • Athinoula A. Martinos Center for Biomedical Imaging, Charlestown · 1 mi away
Ages 18 to 45 · All sexes · Updated Jan 9, 2025 · NCT06763172

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 14 and older · All sexes · Updated Dec 20, 2024 · NCT06655415

Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia

RecruitingPhase 3Healthy volunteers welcome
  • Reviva site, Boston
Ages 18 to 65 · All sexes · Updated Dec 19, 2024 · NCT05184335

Comprehensive Outcomes for After Cancer Health

RecruitingHealthy volunteers welcome
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Dec 11, 2024 · NCT05349227

DNA Analysis of Blood and Tissue from Patients with Lung Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
  • Harvard School of Public Health, Boston
Ages 18 to 120 · All sexes · Updated Nov 29, 2024 · NCT00471978

Molecular and Genetic Analysis of Lung Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Nov 29, 2024 · NCT03029325

Apple Women's Health Study

RecruitingObservational studyHealthy volunteers welcome
  • Harvard T.H. Chan School of Public Health, Boston
Ages 18 and older · All sexes · Updated Jul 3, 2024 · NCT04196595

MyVHL: Patient Natural History Study

RecruitingObservational studyHealthy volunteers welcome
  • VHL Alliance, Boston
All ages · All sexes · Updated Apr 26, 2024 · NCT03749980

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life

RecruitingObservational studyHealthy volunteers welcome
  • Joslin Diabetes Center, Boston
0 Days – 99 Years · All sexes · Updated Nov 21, 2023 · NCT06141434

A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
3 Months · All sexes · Updated Nov 2, 2023 · NCT01873131

Triage Survey for Neurology Research Eligibility

RecruitingObservational studyHealthy volunteers welcome
  • Copley Clinical, Boston
Ages 18 and older · All sexes · Updated Oct 27, 2023 · NCT06104852

Gamma-Music Based Intervention for Mild Alzheimer's Disease

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 50 to 95 · All sexes · Updated Oct 6, 2023 · NCT05984524

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.